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      Dientes supernumerarios: reporte de un caso Translated title: Supernumerary teeth: report of a case

      case-report

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          Abstract

          RESUMEN Los dientes supernumerarios son unidades dentales que numéricamente exceden la cantidad de dientes normal, un fenómeno también conocida como hiperdontia, los dientes supernumerarios más comunes son mesiodens, que ocurren entre los incisivos centrales. El presente artículo tiene como objetivo describir un reporte de caso de una paciente de género femenino, de 21 años de edad, que presenta 13 dientes incluidos, de los cuales 6 son supernumerarios, los mismos que fueron extraídos en dos tiempos quirúrgicos.

          Translated abstract

          ABSTRACT Supernumerary teeth are dental units that numerically exceed the normal number of teeth, a phenomenon also known as hiperdontia. The most common supernumerary teeth are mesiodens, which occur between the central incisors. This article aims to describe a case report of a female patient, 21 yearsold, who has 13 included teeth, of which 6 are supernumerary, thesameones that were extracted in two surgical times.

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          Supernumerary teeth: review of the literature and a survey of 152 cases.

          A review of the literature relating to supernumerary teeth is presented along with a survey of 152 cases. The study population consisted of 152 children who visited the department of Paediatric Dentistry at the Jordan University Hospital. Patients ranged in age from 5 to 15 years. Supernumeraries were detected by clinical examination and radiographs. Males were affected more than females with a sex ratio of 2.2 : 1. Seventy-seven percent of the patients had one supernumerary tooth, 18.4% had double teeth, and 4.6% had three or more supernumeraries. Ninety percent of the supernumerary teeth occurred in the premaxilla, of which 92.8% were in the central incisor region and of these latter 25% were located in the midline. The other 10.4% of the supernumeraries were located in the premolar, canine, molar, and lower central incisor regions. Two cases were of non-syndrome supernumerary teeth. Seventy-five percent of the supernumeraries were conical, 83.1% were in the normal vertical position and 26.5% were erupted. Conical-shaped supernumerary teeth had a significantly higher rate of eruption compared to the tuberculate type.
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            Mutations in the RUNX2 gene in patients with cleidocranial dysplasia.

            Cleidocranial dysplasia (CCD) is a autosomal dominant disorder characterized by skeletal anomalies such as patent fontanels, late closure of cranial sutures with Wormian bones, late erupting secondary dentition, rudimentary clavicles, and short stature. The locus for this disease was mapped to chromosome 6p21. RUNX2 is a member of the runt family of transcription factors and its expression is restricted to developing osteoblasts and a subset of chondrocytes. Mutations in the RUNX2 gene have been shown to cause CCD. Chromosomal translocations, deletions, insertions, nonsense and splice-site mutations, as well as missense mutations of the RUNX2 gene have been described in CCD patients. Although there is a wide spectrum in phenotypic variability ranging from primary dental anomalies to all CCD features plus osteoporosis, no clear phenotype-genotype correlation has been established. However analysis of the three-dimensional structure of the DNA binding runt domain of the RUNX proteins and its interaction with DNA, as well as the cofactor CBFB, start to provide an insight into how missense mutations affect RUNX2 function. Copyright 2002 Wiley-Liss, Inc.
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              Molecular genetics of supernumerary tooth formation.

              Despite advances in the knowledge of tooth morphogenesis and differentiation, relatively little is known about the aetiology and molecular mechanisms underlying supernumerary tooth formation. A small number of supernumerary teeth may be a common developmental dental anomaly, while multiple supernumerary teeth usually have a genetic component and they are sometimes thought to represent a partial third dentition in humans. Mice, which are commonly used for studying tooth development, only exhibit one dentition, with very few mouse models exhibiting supernumerary teeth similar to those in humans. Inactivation of Apc or forced activation of Wnt/β(catenin signalling results in multiple supernumerary tooth formation in both humans and in mice, but the key genes in these pathways are not very clear. Analysis of other model systems with continuous tooth replacement or secondary tooth formation, such as fish, snake, lizard, and ferret, is providing insights into the molecular and cellular mechanisms underlying succesional tooth development, and will assist in the studies on supernumerary tooth formation in humans. This information, together with the advances in stem cell biology and tissue engineering, will pave ways for the tooth regeneration and tooth bioengineering. Copyright © 2011 Wiley-Liss, Inc.
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                Author and article information

                Journal
                odonto
                Avances en Odontoestomatología
                Av Odontoestomatol
                Ediciones Avances, S.L. (Madrid, Madrid, Spain )
                0213-1285
                2340-3152
                December 2022
                : 38
                : 4
                : 151-155
                Affiliations
                [3] Azuay orgnameUniversidad Católica de Cuenca orgdiv1Facultad de Medicina Ecuador
                [1] orgnameEspecialista en patología y cirugía bucal Ecuador
                [2] Azuay orgnameUniversidad Católica de Cuenca orgdiv1Facultad de Medicina Ecuador
                Article
                S0213-12852022000400004 S0213-1285(22)03800400004
                10.4321/s0213-12852022000400004
                9d19f9e2-d096-4315-a15b-8eeb36c77385

                This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 International License.

                History
                : 20 March 2022
                : 03 March 2022
                Page count
                Figures: 0, Tables: 0, Equations: 0, References: 17, Pages: 5
                Product

                SciELO Spain

                Categories
                Artículos

                dientes supernumerarios,Dentistry,evidence-based dentistry,oral surgery,supernumerary teeth,Odontología,odontología basada en la evidencia,cirugía oral

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