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Safety and feasibility of catheter-based local intracoronary vascular endothelial growth factor gene transfer in the prevention of postangioplasty and in-stent restenosis and in the treatment of chronic myocardial ischemia: phase II results of the Kuopio Angiogenesis Trial (KAT).
Marja Hedman
1 ,
Juha Hartikainen ,
Mikko Syvänne ,
Joachim Stjernvall ,
Antti Hedman ,
Antti Kivelä ,
Esko Vanninen ,
Hanna Mussalo ,
Esa Kauppila ,
Sakari Simula ,
Outi Närvänen ,
Arto Rantala ,
Keijo Peuhkurinen ,
Markku S Nieminen ,
Markku Laakso ,
Seppo Ylä-Herttuala
Jun 03 2003
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Abstract
Catheter-based intracoronary vascular endothelial growth factor (VEGF) gene transfer is a potential treatment for coronary heart disease. However, only limited data are available about local VEGF gene transfer given during angioplasty (PTCA) and stenting.