1
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: not found

      Rapid detection of human cytomegalovirus UL97 and UL54 mutations for antiviral resistance in clinical specimens.

      Read this article at

      ScienceOpenPublisherPubMed
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Drug-resistant cytomegalovirus appears during prolonged anti-cytomegalovirus therapy. Assays for human cytomegalovirus viral protein kinase (UL97) and viral DNA polymerase (UL54) gene mutations conferring drug resistance have been used rather than susceptibility assays to assess clinical specimens. In this study a sensitive system for genotype assay of UL97 and UL54 in clinical specimens with as few as six copies/µg of DNA was developed.

          Related collections

          Author and article information

          Journal
          Microbiol Immunol
          Microbiology and immunology
          Wiley
          1348-0421
          0385-5600
          May 2013
          : 57
          : 5
          Affiliations
          [1 ] Department of Virology, University of Toyama, 2630 Sugitani, Toyama 930-0194, Japan.
          Article
          10.1111/1348-0421.12043
          23668613
          9d33648c-7d50-4295-8420-256fa67c8f05
          © 2013 The Societies and Wiley Publishing Asia Pty Ltd.
          History

          Comments

          Comment on this article