The present study assessed the short-term effect of 6 min classroom-based micro-sessions of multi-joint functional high-intensity circuit training (Functional HIIT) performed by students during regular classes on parameters related to functional strength and cardiorespiratory fitness. In this randomized controlled 4-week study, 17 students (11 male; 6 female; age: 11.6 ± 0.2 years) performed 6 min of Functional HIIT (targeting >17 on the Borg scale) 4 days per week during regular school classes and 18 students (11 male; 7 female; age: 11.7 ± 0.3 years) served as control group (CG) without any additional in-class physical activity. The Functional HIIT group completed 86% of all planned sessions (mean duration: 6.0 ± 1.5 min) with a mean RPE of 17.3 ± 2.1. Body height, mass and BMI did not differ between the groups at baseline or between pre- and post-testing ( p > 0.05; eta 2 ≤ 0.218). The performances in lateral jumping ( p < 0.000; part eta 2 = 0.382; Δ% 4.6 ± 8.6), sit-ups ( p < 0.000; part eta 2 = 0.485; Δ% 3.1 ± 8.6) and 20-m sprints ( p < 0.000; part eta 2 = 0.691; Δ% 15.8 ± 5.4) improved in both groups with greater increase following Functional HIIT. No baseline differences and no interaction effects occurred in performance of 6 min run, flexibility, push-ups, balance, and long jump. Classroom-based Functional HIIT sessions, performed 4 days per week during 4 weeks did not improve variables related to aerobic endurance performance but enhanced certain parameters of functional strength in schoolchildren. As time is limited in the educational system of schools, Functional HIIT during regular school classes could offer a new perspective for increasing functional strength in schoolchildren.