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      Nephrotic syndrome in adults.

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          Abstract

          Nephrotic syndrome is an important presentation of glomerular disease characterised by heavy proteinuria, hypoalbuminaemia and oedema. The differential diagnosis of the underlying condition is wide including primary renal disorders and secondary diseases such as malignancy, infection, diabetes and amyloid. Presentations to acute medicine may be with hypervolaemia, complications of the nephrotic state (such as venous thromboembolism), or complications of therapy (such as infection). Early recognition of nephrotic syndrome is possible through simple urinalysis for protein and testing serum albumin, although a high index of suspicion is sometimes required in patients with comorbidities including potentially distracting cardiac or hepatic diseases.

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          Author and article information

          Journal
          Acute Med
          Acute medicine
          1747-4892
          1747-4884
          2018
          : 17
          : 1
          Affiliations
          [1 ] BMedSci MRCP, Renal Unit, Royal London Hospital, Barts Health NHS Trust, London, UK.
          [2 ] PhD MRCP, Renal Unit, Royal London Hospital, Barts Health NHS Trust, London, UK.
          [3 ] MD(Res) FRCPath, Department of Histopathology, Royal London Hospital, Barts Health NHS Trust, London, UK.
          [4 ] MD FRCP, Renal Unit, Royal London Hospital, Barts Health NHS Trust London, UK.
          Article
          29589604

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