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Cycling the synapse: scenic versus direct routes for vesicles.

Neuron

metabolism, Synaptic Vesicles, Synapses, cytology, Neurons, Models, Neurological, Humans, Animals

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      Abstract

      What happens to synaptic vesicles after they release their neurotransmitter content? Recent work on a variety of synaptic systems shows that there is no single answer to this question. Rather, it seems that neurons use a variety of methods to retrieve and reuse synaptic vesicles after they have undergone exocytosis. The challenge now is to establish the molecular mechanisms and to decipher the rules that govern which cycling pathway is used in a given functional context.

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      Journal
      10.1016/j.neuron.2004.09.025
      15473962

      Chemistry

      metabolism, Synaptic Vesicles, Synapses, cytology, Neurons, Models, Neurological, Humans, Animals

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