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      A double-blind, randomised trial of a polyphenolic-rich nail bed balm for chemotherapy-induced onycholysis: the UK polybalm study.

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          Abstract

          Nail damage is common amongst patients receiving chemotherapy causing disfigurement and pain. This investigation evaluated whether a topical balm containing steam-extracted, bioactive polyphenolic-rich herbal oils blended with organic waxes could protect the nails via their reported anti-inflammatory, analgesic, anti-oxidant and anti-microbial properties.

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          Author and article information

          Journal
          Breast Cancer Res. Treat.
          Breast cancer research and treatment
          Springer Science and Business Media LLC
          1573-7217
          0167-6806
          Aug 2018
          : 171
          : 1
          Affiliations
          [1 ] Bedford and Addenbrooke's Cambridge University Hospital Trusts c/o The Primrose Unit, Kempston Rd, Bedford, MK42 9DJ, UK. rt@cancernet.co.uk.
          [2 ] The Primrose Unit Research Office, Bedford Hospital, Kempston Road, Bedford, MK42 9DJ, UK. rt@cancernet.co.uk.
          [3 ] Department of Biological and Exercise Science, Coventry Univerity, Priory Street, Coventry, CV1 5FB, UK. rt@cancernet.co.uk.
          [4 ] The Primrose Unit Research Office, Bedford Hospital, Kempston Road, Bedford, MK42 9DJ, UK.
          [5 ] Department of Mathematics and Statistics, University of Limerick, Limerick, Ireland.
          [6 ] Royal London Hospital for Integrated Medicine, Great Ormond Street, London, WC1N 3HR, UK.
          [7 ] Bedford and Addenbrooke's Cambridge University Hospital Trusts c/o The Primrose Unit, Kempston Rd, Bedford, MK42 9DJ, UK.
          Article
          10.1007/s10549-018-4788-9
          10.1007/s10549-018-4788-9
          29736742
          9e45067b-1b41-4fdd-af70-115d5bd11b4e
          History

          Double-blind clinical trial,Prevention of onycholysis,Prostate cancer,Quality of life,Randomised,Taxane chemotherapy side effect,Breast cancer

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