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      Primary COVID-19 vaccine cycle and booster doses efficacy: analysis of Italian nationwide vaccination campaign

      brief-report
      1 , 2
      The European Journal of Public Health
      Oxford University Press
      COVID-19, SARS-COV-2, Vaccination, Booster

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          Abstract

          We provide here an updated analysis of primary COVID-19 vaccination and vaccine booster doses efficacy, emerging from the ongoing Italian nationwide COVID-19 vaccination campaign. Primary COVID-19 vaccination efficacy was 76-92% within 6 months, decreasing to 34-80% after 6 months. Administration of vaccine booster doses decreased SARS-CoV-2 infections by 65%, COVID-19 related hospitalizations and deaths by 69% and 97% compared to vaccine efficacy after 6 months, but also decreased SARS-CoV-2 infections by 39% compared to vaccine efficacy within 6 months. These results suggest that COVID-19 vaccine booster doses are important for restoring vaccine efficacy and further limiting virus circulation.

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          Author and article information

          Journal
          Eur J Public Health
          Eur J Public Health
          eurpub
          The European Journal of Public Health
          Oxford University Press
          1101-1262
          1464-360X
          03 January 2022
          03 January 2022
          Affiliations
          [1 ] Service of Clinical Governance, Provincial Agency for Social and Sanitary Services , Trento, Italy
          [2 ] Section of Clinical Biochemistry and School of Medicine, University of Verona , Italy
          Author notes
          Corresponding author: Prof. Giuseppe Lippi, Section of Clinical Biochemistry, Department of Neurosciences, Biomedicine and Movement Sciences, P.le L.A Scuro, 10, 37134 Verona, Italy. Phone ++39 045 8124512, Fax ++0458124514, E-mail: giuseppe.lippi@ 123456univr.it
          Article
          ckab220
          10.1093/eurpub/ckab220
          8755380
          34978571
          9e5b6d8a-eea5-45ba-a38d-df830c9d2049
          Published on behalf of the European Society of Cardiology. All rights reserved. © The Author(s) 2022. For permissions, please email: journals.permissions@oup.com.

          This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model ( https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model)

          This article is made available via the PMC Open Access Subset for unrestricted re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the COVID-19 pandemic or until permissions are revoked in writing. Upon expiration of these permissions, PMC is granted a perpetual license to make this article available via PMC and Europe PMC, consistent with existing copyright protections.

          Page count
          Pages: 12
          Product
          Categories
          Short Report
          AcademicSubjects/MED00860
          AcademicSubjects/SOC01210
          AcademicSubjects/SOC02610
          Custom metadata
          accepted-manuscript
          PAP

          Public health
          covid-19,sars-cov-2,vaccination,booster
          Public health
          covid-19, sars-cov-2, vaccination, booster

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