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      Efficient Therapy Planning via Model Reduction for Laser-Induced Interstitial Thermotherapy

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      ScienceOpen
      Laser-Induced Thermotherapy, Therapy Planning, Space-Mapping
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            Abstract

            We investigate the planning of minimally invasive tumor treatments via laser-induced thermotherapy. The goal is to control the laser in order to obtain an optimal treatment, e.g. eradicating the tumor, while leaving as much healthy tissue unharmed as possible. To this end, we define a PDE-constrained optimal control problem. As these problems are usually computationally expensive, we propose a simplified modeling approach using reduced-order models. Numerical results illustrate the viability of our approach.

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            Author and article information

            Journal
            ScienceOpen Posters
            ScienceOpen
            27 April 2018
            Affiliations
            [1 ]Trier University
            [* ]Correspondence: tolle@ 123456uni-trier.de
            Article
            10.14293/P2199-8442.1.SOP-MATH.PYJMWG.v1
            9e676a56-501c-47d4-8138-2c774ed8e798
            Copyright © 2018

            This work has been published open access under Creative Commons Attribution License CC BY 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Conditions, terms of use and publishing policy can be found at www.scienceopen.com.

            History

            Applied mathematics,Applications,Statistics,Data analysis,Mathematics,Mathematical modeling & Computation
            Therapy Planning,Laser-Induced Thermotherapy,Space-Mapping

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