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Efficient Therapy Planning via Model Reduction for Laser-Induced Interstitial Thermotherapy

, 1 , * , 1

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Laser-Induced Thermotherapy, Therapy Planning, Space-Mapping

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      We investigate the planning of minimally invasive tumor treatments via laser-induced thermotherapy. The goal is to control the laser in order to obtain an optimal treatment, e.g. eradicating the tumor, while leaving as much healthy tissue unharmed as possible. To this end, we define a PDE-constrained optimal control problem. As these problems are usually computationally expensive, we propose a simplified modeling approach using reduced-order models. Numerical results illustrate the viability of our approach.

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      [1 ]Trier University
      [* ]Correspondence: tolle@
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      27 April 2018
      Copyright © 2018

      This work has been published open access under Creative Commons Attribution License CC BY 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Conditions, terms of use and publishing policy can be found at


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