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      Corticosteroids in the Management of Sinoatrial Block

      , ,

      Cardiology

      S. Karger AG

      Sinoatrial block, Corticosteroids, Holter

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          Abstract

          This report presented our experience in the treatment of sinoatrial (S-A) conduction disturbances with corticosteroids. Three patients with intermittent second-degree S-A block who failed to respond to atropine and isoproterenol were treated with prednisone for 6–17 weeks. Sustained improvement in S-A conduction following prednisone administration was confirmed by repeated Holter monitoring on and off therapy. Two patients eventually regained permanent sinus rhythm, while therapy led to marked diminution in S-A block in the 3rd patient. The possible mechanisms by which steroids may improve S-A conduction are discussed. Our observation is based on a small case series, each patient serving as his own control, and as such constitutes an indication for further confirmatory studies.

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          Author and article information

          Journal
          CRD
          Cardiology
          10.1159/issn.0008-6312
          Cardiology
          S. Karger AG
          0008-6312
          1421-9751
          1988
          1988
          11 November 2008
          : 75
          : 3
          : 221-225
          Affiliations
          Heart Institute, Haifa Medical Center (Rothschild), Faculty of Medicine, Technion, Haifa, Israel
          Article
          174375 Cardiology 1988;75:221–225
          10.1159/000174375
          3416332
          © 1988 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          Page count
          Pages: 5
          Categories
          Case Report

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