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      Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer.

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          Abstract

          We investigated the efficacy of cetuximab plus irinotecan, fluorouracil, and leucovorin (FOLFIRI) as first-line treatment for metastatic colorectal cancer and sought associations between the mutation status of the KRAS gene in tumors and clinical response to cetuximab.

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          Author and article information

          Journal
          N Engl J Med
          The New England journal of medicine
          Massachusetts Medical Society
          1533-4406
          0028-4793
          Apr 02 2009
          : 360
          : 14
          Affiliations
          [1 ] University Hospital Gasthuisberg, Digestive Oncology Unit, Herestraat 49, 3000 Leuven, Belgium. eric.vancutsem@uz.kuleuven.ac.be
          Article
          360/14/1408
          10.1056/NEJMoa0805019
          19339720
          9ee4e68d-fbda-4cbc-a773-ee3387008606
          2009 Massachusetts Medical Society
          History

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