Fe3O4@piroctone olamine magnetic nanoparticles: Synthesize and therapeutic potential in cutaneous leishmaniasis.

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Abstract

In recent years, magnetic nanoparticles (NMP) as novel materials have been widely used for biomedical, diagnostic and therapeutic purposes like microbial infection therapy. The purpose of this study is to synthesize PO coated iron oxide magnetic nanoparticles (Fe3O4@PO NPs) and their anti-leishmanial effects in vitro and in vivo against cutaneous leishmaniasis.

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Journal

Journal ID (iso-abbrev): Biomed Pharmacother

Title: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Publisher: Elsevier BV

ISSN (Electronic): 1950-6007

ISSN (Print): 0753-3322

Publication date (Electronic): Jul 2021

Volume: 139

Affiliations

[1 ] Faculty of Science, University of Tabuk, Tabuk, Saudi Arabia.

[2 ] Department of Microbiology, College of Medicine, University of Thiqar, Thiqar, Iraq.

[3 ] Department of Zoology, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia.

[4 ] Department of Biological Science, Faculty of Science and Humanities, Shaqra University, P.O. Box 1040, Ad-Dawadimi 11911, Saudi Arabia; Alghad International Colleges for Applied Medical Science, Tabuk 47913, Saudi Arabia.

[5 ] Department of Community Medicine, Lorestan University of Medical Sciences, Khorramabad, Iran.

[6 ] Pharmaceutics Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran.

[7 ] Razi Herbal Medicines Research Center, Lorestan University of Medical Sciences, Khorramabad, Iran. Electronic address: dmahmodvand@gmail.com.

Article

Publisher Item ID: S0753-3322(21)00351-6

DOI: 10.1016/j.biopha.2021.111566

PubMed ID: 33839494

SO-VID: 9ef6e095-0de7-4930-9ed4-f8d511db77e2

History

Keywords: Leishmania major,In vivo,In vitro,Cytotoxicity,Amastigote,Nitric oxide

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Keywords: Leishmania major, In vivo, In vitro, Cytotoxicity, Amastigote, Nitric oxide

Fe3O4@piroctone olamine magnetic nanoparticles: Synthesize and therapeutic potential in cutaneous leishmaniasis.

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cGMP: Generators, Effectors and Therapeutic Implications Conference

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