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      Impact of the exon 3-deleted growth hormone (GH) receptor polymorphism on baseline height and the growth response to recombinant human GH therapy in GH-deficient (GHD) and non-GHD children with short stature: a systematic review and meta-analysis.

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          Abstract

          The exon-3 deleted GH receptor (GHR(d3)) polymorphism is associated with an increased growth response to recombinant human GH (rhGH) therapy in some, but not all, studies in GH-deficient (GHD) and non-GHD children with short stature.

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          Author and article information

          Journal
          J Clin Endocrinol Metab
          The Journal of clinical endocrinology and metabolism
          The Endocrine Society
          1945-7197
          0021-972X
          Oct 2009
          : 94
          : 10
          Affiliations
          [1 ] Department of Endocrinology and Metabolic Diseases, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.
          Article
          jc.2009-0425
          10.1210/jc.2009-0425
          19584188
          9f079e12-b3ba-4dbf-83a0-e2ab31af1159
          History

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