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      Practical cut-offs for visual rating scales of medial temporal, frontal and posterior atrophy in Alzheimer's disease and mild cognitive impairment.

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          Abstract

          Atrophy in the medial temporal lobe, frontal lobe and posterior cortex can be measured with visual rating scales such as the medial temporal atrophy (MTA), global cortical atrophy - frontal subscale (GCA-F) and posterior atrophy (PA) scales, respectively. However, practical cut-offs are urgently needed, especially now that different presentations of Alzheimer's disease (AD) are included in the revised diagnostic criteria.

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          Author and article information

          Journal
          J. Intern. Med.
          Journal of internal medicine
          1365-2796
          0954-6820
          Sep 2015
          : 278
          : 3
          Affiliations
          [1 ] Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Division of Clinical Geriatrics, Stockholm, Sweden.
          [2 ] Department of Clinical Science, Intervention and Technology, Division of Medical Imaging and Technology, Karolinska Institutet, Stockholm, Sweden.
          [3 ] Department of Radiology, Karolinska University Hospital, Stockholm, Sweden.
          [4 ] Department of Radiology, Oncology and Radiation Science, Uppsala University, Uppsala, Sweden.
          [5 ] Institute of Gerontology and Geriatrics, University of Perugia, Perugia, Italy.
          [6 ] INSERM U 558, University of Toulouse, Toulouse, France.
          [7 ] 3rd Department of Neurology, Aristoteleion Panepistimeion Thessalonikis, Thessaloniki, Greece.
          [8 ] Medical University of Lodz, Lodz, Poland.
          [9 ] University of Eastern Finland, University Hospital of Kuopio, Kuopio, Finland.
          [10 ] Department of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK.
          [11 ] Institute of Psychiatry, King's College London, London, UK.
          [12 ] NIHR Biomedical Research Centre for Mental Health, London, UK.
          [13 ] NIHR Biomedical Research Unit for Dementia, London, UK.
          Article
          10.1111/joim.12358
          25752192
          9f1b4d20-2f48-4b00-a705-c8360d3eb479
          © 2015 The Association for the Publication of the Journal of Internal Medicine.
          History

          Alzheimer's disease,frontal atrophy,medial temporal atrophy,mild cognitive impairment,posterior atrophy,visual rating scales

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