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      Cimetidine-Induced Climacteric Symptoms in a Young Man Maintained on Chronic Hemodialysis


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          We present the case of a young man on maintenance hemodialysis who developed frequent episodes of ‘fluttering, racing heartbeats’, hot flashes, profuse sweating, anxiety, dizziness, and shortness of breath. These symptoms started approximately 1 month after taking cimetidine 400 mg/day with an occasional extra dose. His workup included a total of 72 h of cardiac monitoring, two-dimensional echocardiogram, and thyroid function tests, all of which were essentially unremarkable. When the drug cimetidine was temporarily discontinued, and on another occasion after the drug was totally withdrawn, the patient noticed marked improvement in his symptoms at 48 h with total resolution on the 5th day after discontinuation. This is the 2nd such case reported in the literature.

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          Cimetidine toxic reactions masquerading as delirium tremens


            Author and article information

            Am J Nephrol
            American Journal of Nephrology
            S. Karger AG
            December 1998
            09 December 1998
            : 18
            : 6
            : 538-540
            Division of Nephrology, St. Louis University Health Sciences Center, St. Louis, Mo., USA
            13402 Am J Nephrol 1998;18:538–540
            © 1998 S. Karger AG, Basel

            Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

            Page count
            References: 20, Pages: 3
            Self URI (application/pdf): https://www.karger.com/Article/Pdf/13402
            Self URI (text/html): https://www.karger.com/Article/FullText/13402
            Self URI (journal page): https://www.karger.com/SubjectArea/Nephrology
            Case Report

            Cardiovascular Medicine,Nephrology
            Renal failure,Cimetidine, dialysis,Side effects, cimetidine
            Cardiovascular Medicine, Nephrology
            Renal failure, Cimetidine, dialysis, Side effects, cimetidine


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