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Prevalence of Trichomonas vaginalis isolates with resistance to metronidazole and tinidazole.

Author(s): Jane R. Schwebke, Oscar Barrientes

Publication date: 2006-11-30

Journal: Antimicrobial Agents and Chemotherapy

Keywords: Animals, Antitrichomonal Agents, pharmacology, Drug Resistance, Female, Humans, Metronidazole, Prevalence, Tinidazole, Trichomonas vaginalis, drug effects, isolation & purification

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Abstract

Clinical isolates of Trichomonas vaginalis were obtained from women consecutively enrolled in a study of partner notification. Testing of susceptibility to metronidazole and tinidazole was performed. Resistance to metronidazole and tinidazole was present in 17/178 (9.6%) and 1/178 (0.56%) strains, respectively. In vitro resistance was poorly correlated with clinical response to treatment.

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PubMed ID:: 17000740

PMC ID:: 1693974

DOI:: 10.1128/AAC.00814-06

ScienceOpen disciplines: Chemistry

Keywords: Animals,Antitrichomonal Agents,pharmacology,Drug Resistance,Female,Humans,Metronidazole,Prevalence,Tinidazole,Trichomonas vaginalis,drug effects,isolation & purification

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ScienceOpen disciplines: Chemistry

Keywords: Animals, Antitrichomonal Agents, pharmacology, Drug Resistance, Female, Humans, Metronidazole, Prevalence, Tinidazole, Trichomonas vaginalis, drug effects, isolation & purification

Prevalence of Trichomonas vaginalis isolates with resistance to metronidazole and tinidazole.

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