Collagen barrier membranes adsorb growth factors liberated from autogenous bone chips.

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Abstract

Collagen membranes serve as barriers to separate bone grafts from soft tissues. Bone grafts harvested with a bone scraper release growth factors activating transforming growth factor-β (TGF-β) signaling in mesenchymal cells. The aim of the present pilot study was to determine whether collagen membranes adsorb molecules from bone-conditioned medium (BCM) with the capacity to provoke the expression of TGF-β target genes in vitro.

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Journal

Journal ID (iso-abbrev): Clin Oral Implants Res

Title: Clinical oral implants research

Publisher: Wiley-Blackwell

ISSN (Electronic): 1600-0501

ISSN (Print): 0905-7161

Publication date (Electronic): Feb 2017

Volume: 28

Issue: 2

Affiliations

[1 ] Laboratory of Oral Cell Biology, School of Dental Medicine, University of Bern, Bern, Switzerland.

[2 ] Department of Oral Surgery and Stomatology, School of Dental Medicine, University of Bern, Bern, Switzerland.

[3 ] Department of Oral and Maxillofacial Surgery, School of Dental Medicine, Universitat Internacional de Catalunya, Barcelona, Spain.

[4 ] Department of Cranio-Maxillofacial Surgery, Bern University Hospital, Inselspital, Bern, Switzerland.

[5 ] Robert K. Schenk Laboratory of Oral Histology, School of Dental Medicine, University of Bern, Bern, Switzerland.

[6 ] Department of Oral Biology, Medical University of Vienna, Vienna, Austria.

Article

DOI: 10.1111/clr.12789

PubMed ID: 26818588

SO-VID: 9fcca369-5e0b-4704-b886-1452785e266c

History

Keywords: autologous bone,bone graft,bone-conditioned medium,collagen barrier membrane,dental implant,guided bone regeneration,transforming growth factor-β

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Keywords: autologous bone, bone graft, bone-conditioned medium, collagen barrier membrane, dental implant, guided bone regeneration, transforming growth factor-β

Collagen barrier membranes adsorb growth factors liberated from autogenous bone chips.

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Animal models of intrauterine growth restriction (IUGR)

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