Shinsuke Mohri: Role: ConceptualizationRole: Data curationRole: InvestigationRole: MethodologyRole:
Writing – original draft
Haruya Takahashi: Role: Data curationRole: Funding acquisitionRole: InvestigationRole: MethodologyRole:
Writing – original draft
Maiko Sakai: Role: Data curationRole: Methodology
Shingo Takahashi: Role: Resources
Naoko Waki: Role: Resources
Koichi Aizawa: Role: Resources
Hiroyuki Suganuma: Role: Resources
Takeshi Ara: Role: Investigation
Yasuki Matsumura: Role: ConceptualizationRole: Funding acquisitionRole: Writing – review & editing
Daisuke Shibata: Role: ConceptualizationRole: Funding acquisitionRole: Writing – review & editing
Tsuyoshi Goto: Role: ConceptualizationRole: Funding acquisitionRole: InvestigationRole: Writing –
review & editing
Teruo Kawada: Role: ConceptualizationRole: Funding acquisitionRole: InvestigationRole: Project administrationRole:
SupervisionRole: Writing – review & editing
Nobuyuki Takahashi: Role: Editor
Journal ID (nlm-ta): PLoS One
Journal ID (iso-abbrev): PLoS ONE
Journal ID (publisher-id): plos
Journal ID (pmc): plosone
Title:
PLoS ONE
Publisher:
Public Library of Science
(San Francisco, CA USA
)
ISSN
(Electronic):
1932-6203
Publication date
(Electronic):
12
January
2018
Publication date Collection: 2018
Volume: 13
Issue: 1
Electronic Location Identifier: e0191203
Affiliations
[1
]
Laboratory of Molecular Function of Food, Graduate School of Agriculture, Kyoto University,
Uji, Kyoto, Japan
[2
]
KAGOME Tomato Discoveries Laboratory, Graduate School of Agriculture, Kyoto University,
Kyoto, Japan
[3
]
Innovation Division, KAGOME CO., LTD., Tochigi, Japan
[4
]
Laboratory of Quality Analysis and Assessment, Graduate School of Agriculture, Kyoto
University, Uji, Kyoto, Japan
[5
]
Kazusa DNA Research Institutes, Kazusa-Kamatari, Kisarazu, Chiba, Japan
[6
]
Research Unit for Physiological Chemistry, Kyoto University, Kyoto, Japan
Tokyo University of Agriculture, JAPAN
Author notes
Competing Interests: In this study, the authors received funding by KAGOME CO., LTD. This does not alter
the authors' adherence to PLOS ONE policies on sharing data and materials.
Article
Publisher ID:
PONE-D-17-31545
DOI: 10.1371/journal.pone.0191203
PMC ID: 5766234
PubMed ID: 29329333
SO-VID: a00d0b83-9693-4906-9a49-36a803df46e1
Copyright © © 2018 Mohri et al
License:
This is an open access article distributed under the terms of the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided
the original author and source are credited.
Funded by: Japan Society for the Promotion of Science (JP)
Award ID: 16H02551
Award Recipient
:
Teruo Kawada
Funded by: Japan Society for the Promotion of Science (JP)
Award ID: 16K14927
Award Recipient
:
Teruo Kawada
Funded by: Japan Society for the Promotion of Science (JP)
Award ID: 16K07734
Award Recipient
:
Tsuyoshi Goto
Funded by: Japan Society for the Promotion of Science (JP)
Award ID: 16K18703
Award Recipient
:
Haruya Takahashi
This study was funded by KAGOME CO., LTD. The funders had no role in study design,
data collection and analysis, decision to publish, or preparation of the manuscript.
Subject:
Research Article
Subject:
Biology and Life Sciences
Subject:
Organisms
Subject:
Eukaryota
Subject:
Plants
Subject:
Fruits
Subject:
Tomatoes
Subject:
Biology and Life Sciences
Subject:
Cell Biology
Subject:
Cellular Types
Subject:
Animal Cells
Subject:
Blood Cells
Subject:
White Blood Cells
Subject:
Macrophages
Subject:
Biology and Life Sciences
Subject:
Cell Biology
Subject:
Cellular Types
Subject:
Animal Cells
Subject:
Immune Cells
Subject:
White Blood Cells
Subject:
Macrophages
Subject:
Biology and Life Sciences
Subject:
Immunology
Subject:
Immune Cells
Subject:
White Blood Cells
Subject:
Macrophages
Subject:
Medicine and Health Sciences
Subject:
Immunology
Subject:
Immune Cells
Subject:
White Blood Cells
Subject:
Macrophages
Subject:
Research and Analysis Methods
Subject:
Chromatographic Techniques
Subject:
Liquid Chromatography
Subject:
Liquid Chromatography-Mass Spectrometry
Subject:
Physical Sciences
Subject:
Chemistry
Subject:
Analytical Chemistry
Subject:
Mass Spectrometry
Subject:
Liquid Chromatography-Mass Spectrometry
Subject:
Research and Analysis Methods
Subject:
Spectrum Analysis Techniques
Subject:
Mass Spectrometry
Subject:
Liquid Chromatography-Mass Spectrometry
Subject:
Biology and Life Sciences
Subject:
Immunology
Subject:
Immune Response
Subject:
Inflammation
Subject:
Medicine and Health Sciences
Subject:
Immunology
Subject:
Immune Response
Subject:
Inflammation
Subject:
Medicine and Health Sciences
Subject:
Diagnostic Medicine
Subject:
Signs and Symptoms
Subject:
Inflammation
Subject:
Medicine and Health Sciences
Subject:
Pathology and Laboratory Medicine
Subject:
Signs and Symptoms
Subject:
Inflammation
Subject:
Research and Analysis Methods
Subject:
Chromatographic Techniques
Subject:
Liquid Chromatography
Subject:
High Performance Liquid Chromatography
Subject:
Biology and Life Sciences
Subject:
Anatomy
Subject:
Biological Tissue
Subject:
Adipose Tissue
Subject:
Medicine and Health Sciences
Subject:
Anatomy
Subject:
Biological Tissue
Subject:
Adipose Tissue
Subject:
Biology and Life Sciences
Subject:
Physiology
Subject:
Physiological Processes
Subject:
Secretion
Subject:
Medicine and Health Sciences
Subject:
Physiology
Subject:
Physiological Processes
Subject:
Secretion
Subject:
Biology and Life Sciences
Subject:
Physiology
Subject:
Physiological Parameters
Subject:
Body Weight
Subject:
Obesity
Subject:
Medicine and Health Sciences
Subject:
Physiology
Subject:
Physiological Parameters
Subject:
Body Weight
Subject:
Obesity