Mass spectral studies on 1-n-pentyl-3-(1-naphthoyl)indole (JWH-018), three deuterium-labeled analogues and the inverse isomer 1-naphthoyl-3-n-pentylindole.

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Abstract

A number of synthetic cannabinoids such as the 1-alkyl-3-acylindoles are the target of significant designer drug activity. One of the first waves of these compounds identified in clandestine samples was 1-n-pentyl-3-(1-naphthoyl)indole, JWH-018. These totally synthetic molecules can be prepared in a number of regioisomeric forms.

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Journal

Journal ID (iso-abbrev): Rapid Commun. Mass Spectrom.

Title: Rapid communications in mass spectrometry : RCM

ISSN (Electronic): 1097-0231

ISSN (Print): 0951-4198

Publication date (Electronic): May 15 2015

Volume: 29

Issue: 9

Affiliations

[1 ] Department of Drug Discovery and Development, Harrison School of Pharmacy, Auburn University, Auburn, AL, 36849, USA.

[2 ] Department of Pharmaceutical Analytical Chemistry, Faculty of Pharmacy, Alexandria University, Alexandria, 21521, Egypt.

Article

DOI: 10.1002/rcm.7171

PubMed ID: 26377015

SO-VID: a0112016-a07f-4339-b9c7-45d39acacbad

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