12
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: not found

      Serological detection of verocytotoxin-producing Escherichia coli in patients with haemolytic uraemic syndrome in western Europe.

      European Journal of Clinical Microbiology & Infectious Diseases
      Antibodies, Bacterial, blood, Bacterial Toxins, biosynthesis, Belgium, Escherichia coli, classification, immunology, isolation & purification, pathogenicity, Escherichia coli Infections, microbiology, Female, Germany, Hemolytic-Uremic Syndrome, Humans, Immunoblotting, Immunoenzyme Techniques, Lipopolysaccharides, Male, Netherlands, O Antigens, Polysaccharides, Bacterial, Serotyping, Shiga Toxin 1

      Read this article at

      ScienceOpenPubMed
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Sera from 45 patients from The Netherlands, Germany and Belgium who had a clinical diagnosis of haemolytic uraemic syndrome (HUS) were screened for antibodies to the lipopolysaccharide (LPS) of Escherichia coli producing Verocytotoxin (VTEC). Sera from 43 family contacts and 34 control patients were also examined. Using the techniques of EIA and immunoblotting, antibodies to the LPS of Escherichia coli O157 were found in 28 patients, and to the LPS of serogroups O115 and O145 in one patient and one family member respectively. The results of our study suggest that VTEC, and in particular Escherichia coli O157, might be a significant cause of HUS in Western Europe.

          Related collections

          Author and article information

          Comments

          Comment on this article