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      Peripheral Arterial Disease Is Not Associated with an Increased Prevalence of Intradialytic Cramps in Patients on Maintenance Hemodialysis

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          Background/Aims: Peripheral arterial disease (PAD) has been suggested as a contributing factor to the development of intradialytic muscle cramps in patients on maintenance hemodialysis. Methods: To test this hypothesis, 122 patients from two dialysis centers were studied. The presence of PAD was determined by measurement of the ankle-brachial index (ABI) in the lower extremities of patients pre- and postdialysis. The experience of intradialytic cramps was assessed using patient history and review of medical records. Results: PAD defined as a predialysis ABI ≤0.90 had an overall prevalence of 16.4% among patients studied. The prevalence of PAD was age-dependent, reaching 37.5% in patients 80–89 years old. Intradialytic muscle cramps were common, with 52.1% of patients reporting cramps within the previous two months, but there was no relationship between cramps during dialysis and PAD (p > 0.05). Conclusions: PAD was common in hemodialysis patients, but there was no association between the presence of PAD and the prevalence of intradialytic muscle cramps.

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          Most cited references 2

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          Treatment of dialysis-related muscle cramps with hypertonic dextrose

           C. Neal (1981)
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            Dialysis symptoms and stabilization in long-term dialysis. Practical application of the CUSUM plot

             Maria A Rosa (1980)

              Author and article information

              Am J Nephrol
              American Journal of Nephrology
              S. Karger AG
              December 2002
              07 October 2002
              : 22
              : 5-6
              : 491-496
              aDepartment of Medicine, Harbor-UCLA Medical Center, Torrance, Calif.; bSigma Tau Research, Gaithersburg, Md., and cColorado Prevention Center, University of Colorado Health Sciences Center, Denver, Colo., USA
              65285 Am J Nephrol 2002;22:491–496
              © 2002 S. Karger AG, Basel

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              Tables: 4, References: 27, Pages: 6
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