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      3T MRI investigation of cardiac left ventricular structure and function in a UK population: The tayside screening for the prevention of cardiac events (TASCFORCE) study

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          Abstract

          Purpose

          To scan a volunteer population using 3.0T magnetic resonance imaging (MRI). MRI of the left ventricular (LV) structure and function in healthy volunteers has been reported extensively at 1.5T.

          Materials and Methods

          A population of 1528 volunteers was scanned. A standardized approach was taken to acquire steady‐state free precession (SSFP) LV data in the short‐axis plane, and images were quantified using commercial software. Six observers undertook the segmentation analysis.

          Results

          Mean values (±standard deviation, SD) were: ejection fraction (EF) = 69 ± 6%, end diastolic volume index (EDVI) = 71 ± 13 ml/m 2, end systolic volume index (ESVI) = 22 ± 7 ml/m 2, stroke volume index (SVI) = 49 ± 8 ml/m 2, and LV mass index (LVMI) = 55 ± 12 g/m 2. The mean EF was slightly larger for females (69%) than for males (68%), but all other variables were smaller for females (EDVI 68v77 ml/m 2, ESVI 21v25 ml/m 2, SVI 46v52 ml/m 2, LVMI 49v64 g/m 2, all P < 0.05). The mean LV volume data mostly decreased with each age decade (EDVI males: –2.9 ± 1.3 ml/m 2, females: –3.1 ± 0.8 ml/m 2; ESVI males: –1.3 ± 0.7 ml/m 2, females: –1.7 ± 0.5 ml/m 2; SVI males: –1.7 ± 0.9 ml/m 2, females: –1.4 ± 0.6 ml/m 2; LVMI males: –1.6 ± 1.1 g/m 2, females: –0.2 ± 0.6 g/m 2) but the mean EF was virtually stable in males (0.6 ± 0.6%) and rose slightly in females (1.2 ± 0.5%) with age.

          Conclusion

          LV reference ranges are provided in this population‐based MR study at 3.0T. The variables are similar to those described at 1.5T, including variations with age and gender. These data may help to support future population‐based MR research studies that involve the use of 3.0T MRI scanners. J. Magn. Reson. Imaging 2016;44:1186–1196.

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          Most cited references 26

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              Standardized image interpretation and post processing in cardiovascular magnetic resonance: Society for Cardiovascular Magnetic Resonance (SCMR) Board of Trustees Task Force on Standardized Post Processing

              With mounting data on its accuracy and prognostic value, cardiovascular magnetic resonance (CMR) is becoming an increasingly important diagnostic tool with growing utility in clinical routine. Given its versatility and wide range of quantitative parameters, however, agreement on specific standards for the interpretation and post-processing of CMR studies is required to ensure consistent quality and reproducibility of CMR reports. This document addresses this need by providing consensus recommendations developed by the Task Force for Post Processing of the Society for Cardiovascular MR (SCMR). The aim of the task force is to recommend requirements and standards for image interpretation and post processing enabling qualitative and quantitative evaluation of CMR images. Furthermore, pitfalls of CMR image analysis are discussed where appropriate.
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                Author and article information

                Contributors
                ghouston@nhs.net
                Journal
                J Magn Reson Imaging
                J Magn Reson Imaging
                10.1002/(ISSN)1522-2586
                JMRI
                Journal of Magnetic Resonance Imaging
                John Wiley and Sons Inc. (Hoboken )
                1053-1807
                1522-2586
                03 May 2016
                November 2016
                : 44
                : 5 ( doiID: 10.1002/jmri.v44.5 )
                : 1186-1196
                Affiliations
                [ 1 ] NHS Tayside Clinical RadiologyNinewells Hospital DundeeUK
                [ 2 ] NHS Tayside Medical PhysicsNinewells Hospital DundeeUK
                [ 3 ]University of Dundee School of Medicine DundeeUK
                [ 4 ] Department of Family and Community MedicineUniversity of Toronto TorontoCanada
                [ 5 ] Department of Research and InnovationNorth York General Hospital TorontoCanada
                [ 6 ] Department of Clinical RadiologyUniversity Hospital of Wales UK
                Author notes
                [* ]Address reprint requests to: J.G.H., Department of Clinical Radiology, Ninewells Hospital, Dundee, DD1 9SY, UK. E‐mail: ghouston@ 123456nhs.net
                JMRI25267
                10.1002/jmri.25267
                5082537
                27143317
                © 2016 The Authors Journal of Magnetic Resonance Imaging published by Wiley Periodicals, Inc. on behalf of International Society for Magnetic Resonance in Medicine.

                This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

                Counts
                Figures: 2, Tables: 7, Pages: 11, Words: 5285
                Product
                Funding
                Funded by: Souter Charitable Trust, and Chest, Heart and Stroke Scotland
                Funded by: Wellcome Trust
                Award ID: WT 085664 (Clinical Research Fellowship to J.W‐McC.)
                Categories
                Original Research
                Original Research
                Cardiac
                Custom metadata
                2.0
                jmri25267
                November 2016
                Converter:WILEY_ML3GV2_TO_NLMPMC version:4.9.6 mode:remove_FC converted:27.10.2016

                Radiology & Imaging

                population, left ventricle, 3.0t, mri, cardiac

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