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      Why do we need to regulate autophagy (and how can we do it)? A cartoon depiction

      Autophagy

      Taylor & Francis

      Autophagosome, frequency, macroautophagy, number, regulation, size

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          ABSTRACT

          In a recent issue of this journal I attempted to explain the purpose of macroautophagy/autophagy to a non-specialist audience through the use of cartoons. In the present article, I am continuing this approach by considering the topic of autophagy regulation—why does the cell need to modulate the autophagic response, and what are the basic morphological mechanisms that can be used to attain different levels of autophagy activity?

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          Author and article information

          Journal
          Autophagy
          Autophagy
          KAUP
          kaup20
          Autophagy
          Taylor & Francis
          1554-8627
          1554-8635
          2018
          9 September 2018
          : 14
          : 10
          : 1661-1664
          Affiliations
          Life Sciences Institute, University of Michigan , Ann Arbor, MI, USA
          Author notes
          CONTACT Daniel J. Klionsky klionsky@ 123456umich.edu Life Sciences Institute, University of Michigan , Ann Arbor, MI 48109, USA
          Article
          PMC6135627 PMC6135627 6135627 1511218
          10.1080/15548627.2018.1511218
          6135627
          30129812
          © 2018 Informa UK Limited, trading as Taylor & Francis Group
          Page count
          Figures: 7, References: 5, Pages: 4
          Funding
          Funded by: National Institute of General Medical Sciences 10.13039/100000057
          Award ID: GM053396
          This work was supported by the National Institute of General Medical Sciences [GM053396].
          Categories
          Editor’s Corner

          frequency, size, Autophagosome, regulation, macroautophagy, number

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