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Resazurin Microtiter Assay Plate: Simple and Inexpensive Method for Detection of Drug Resistance in Mycobacterium tuberculosis
August 01 2002
August 01 2002
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Abstract
A method for detecting multidrug-resistant Mycobacterium tuberculosis by using a reduction
of resazurin is described. Eighty clinical isolates were evaluated against isoniazid
and rifampin; results at 7 days were compared with those of the proportion method.
Specificity and sensitivity were excellent. The method is simple, inexpensive, and
rapid and might be used with other antituberculosis drugs.