19
views
0
recommends
+1 Recommend
1 collections
    0
    shares

      Call for Papers: Green Renal Replacement Therapy: Caring for the Environment

      Submit here before July 31, 2024

      About Blood Purification: 3.0 Impact Factor I 5.6 CiteScore I 0.83 Scimago Journal & Country Rank (SJR)

      • Record: found
      • Abstract: found
      • Article: found

      Diagnostic Significance of Bone Marrow Biopsy in Chronic Renal Disease

      research-article
      , , ,
      Nephron
      S. Karger AG
      Renal failure, Hemodialysis, Anemia of uremia, Renal osteodystrophy

      Read this article at

      ScienceOpenPublisherPubMed
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          34 patients with chronic renal failure, 20 on periodic hemodialysis and 14 without dialysis, were evaluated for defects in iron stores, folic acid deficiency and renal osteodystrophy. A high incidence of abnormalities in iron stores was observed on bone marrow biopsy. The estimation of iron stores by means of serum iron and percent saturation measurements were unreliable. Significant folic acid depletion was an infrequent finding. The biochemical measurement of serum calcium or inorganic phosphorus had little predictive value in terms of renal osteodystrophy as demonstrated on bone marrow biopsy while serum alkaline phosphatase changes were of limited usefulness. Dialyzed patients generally had lesser abnormalities in iron studies as well as in bone assessments. The study suggests that bone marrow biopsy is a more reliable method of evaluating patients with chronic renal failure for iron abnormalities as well as for osteodystrophy as compared to the usually employed laboratory tests.

          Related collections

          Author and article information

          Journal
          NEF
          Nephron
          10.1159/issn.1660-8151
          Nephron
          S. Karger AG
          1660-8151
          2235-3186
          1974
          1974
          28 November 2008
          : 12
          : 2
          : 81-93
          Affiliations
          Hematology and Renal Divisions, Department of Medicine, and Department of Pathology, Mount Sinai Hospital Medical Center, University of Health Sciences/The Chicago Medical School, Chicago, Ill.
          Article
          180270 Nephron 1974;12:81–93
          10.1159/000180270
          4837747
          a196c727-9eec-4b48-aec4-a6d6f1f07525
          © 1974 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          History
          : 18 March 1973
          : 19 June 1973
          Page count
          Pages: 13
          Categories
          Paper

          Cardiovascular Medicine,Nephrology
          Hemodialysis,Renal failure,Renal osteodystrophy,Anemia of uremia

          Comments

          Comment on this article