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      Medications for the treatment of obesity in adolescents

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          Abstract

          While there are eight medications/combinations approved for the treatment of obesity in adults, the options for the treatment of obesity in adolescents remain limited. Evidence for obesity medication use in adolescents is limited due to the relatively small number of clinical trials that have been completed and the few adolescents that have been included in many of the trials. The goal of this review will be to present the current evidence for the medications approved for adolescents, medications not approved for adolescents but have adolescent data, and medications approved for adults with the prospect for use in adolescents. We will also discuss current limitations and next steps in the exploration of future treatment options.

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          Prevalence of Obesity Among Adults and Youth: United States, 2015-2016.

          Craig Hales, Margaret Carroll, Cheryl D Fryar … (2017)
          Obesity is associated with serious health risks. Monitoring obesity prevalence is relevant for public health programs that focus on reducing or preventing obesity. Between 2003–2004 and 2013–2014, there were no significant changes in childhood obesity prevalence, but adults showed an increasing trend. This report provides the most recent national estimates from 2015–2016 on obesity prevalence by sex, age, and race and Hispanic origin, and overall estimates from 1999–2000 through 2015–2016.
          Article 0 comments Cited 438 times – based on 0 reviews     Review now
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            Pharmacological management of obesity: an endocrine Society clinical practice guideline.

            Caroline M Apovian, Louis Aronne, Daniel H. Bessesen … (2015)
            To formulate clinical practice guidelines for the pharmacological management of obesity.
            Article 0 comments Cited 330 times – based on 0 reviews     Review now
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              Pediatric Obesity—Assessment, Treatment, and Prevention: An Endocrine Society Clinical Practice Guideline

              Dennis M Styne, Ismaa Farooqi, M Murad … (2017)
              The European Society of Endocrinology and the Pediatric Endocrine Society. This guideline was funded by the Endocrine Society.
              Article 0 comments Cited 286 times – based on 0 reviews     Review now
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                Author and article information

                Contributors
                Kaylee Woodard
                Logan Louque
                Daniel S. Hsia:
                ORCID: https://orcid.org/0000-0003-2832-3429
                Journal
                Journal ID (nlm-ta): Ther Adv Endocrinol Metab
                Journal ID (iso-abbrev): Ther Adv Endocrinol Metab
                Journal ID (publisher-id): TAE
                Journal ID (hwp): sptae
                Title: Therapeutic Advances in Endocrinology and Metabolism
                Publisher: SAGE Publications (Sage UK: London, England )
                ISSN (Print): 2042-0188
                ISSN (Electronic): 2042-0196
                Publication date (Electronic): 27 May 2020
                Publication date Collection: 2020
                Volume: 11
                Electronic Location Identifier: 2042018820918789
                Affiliations
                [1-2042018820918789]Pennington Biomedical Research Center, Clinical Trials Unit, Baton Rouge, LA, USA
                [2-2042018820918789]Pennington Biomedical Research Center, Clinical Trials Unit, Baton Rouge, LA, USA
                [3-2042018820918789]Pennington Biomedical Research Center, Clinical Trials Unit, 6400 Perkins Rd., Baton Rouge, LA 70808-4124, USA
                Author notes
                Author information
                https://orcid.org/0000-0003-2832-3429
                Article
                Publisher ID: 10.1177_2042018820918789
                DOI: 10.1177/2042018820918789
                PMC ID: 7257846
                SO-VID: a1b26946-310e-4e62-a41e-d8b5ff29bf22
                Copyright © © The Author(s), 2020
                License:

                This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License ( https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages ( https://us.sagepub.com/en-us/nam/open-access-at-sage).

                History
                Date received : 22 October 2019
                Date accepted : 21 March 2020
                Funding
                Funded by: NIH Office of the Director, FundRef https://doi.org/10.13039/100000052;
                Award ID: 8UG1OD024959
                Categories
                Subject: Review
                Custom metadata
                cover-date January-December 2020
                typesetter ts1

                Keywords: adolescents,medications,obesity
                Data availability:
                Keywords: adolescents, medications, obesity

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