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      Study on postpartum estrus of guinea pigs ( Cavia cobaya) using Anredera cordifolia leaf extract

      research-article
      , ,
      Veterinary World
      Veterinary World
      Anredera cordifolia, Cavia cobaya, estrus cycle, postpartum

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          Abstract

          Aim:

          The purpose of this study was to determine the postpartum estrus cycle of guinea pigs ( Cavia cobaya) using Anredera cordifolia leaf extract.

          Materials and Methods:

          Materials used were 8 males and 8 females of C. cobaya with body weight ranged 400-450 g. Mating ratio applied was 1:1. Treatments given were 0, 10, 50 and 90 mg of A. cordifolia leaf extract/head, designated as T0, T1, T2 and T3, respectively. Two females were subjected for each treatment. A. cordifolia leaf extract was administered orally from 10 days prepartum to 10 days postpartum. Observation of mating behavior, vulva morphology, and vaginal smear preparation was done in the afternoon for 10 days subsequence postpartum. Data were analyzed by univariate method and descriptively.

          Results:

          The results showed that the addition of A. cordifolia leaf extract 50 mg orally could accelerate the time of postpartum estrus based on the average frequency of mating behavior consisting of behavioral approach, allow the buck to sniffing her, mating positions, standing heat, lordosis position, and copulation. During estrus, vulva morphology was red color, had much mucus and no thin membrane covering vagina. There were a lot of superficial cells on vagina.

          Conclusion:

          The best treatment to accelerate occurring postpartum estrus was the addition of A. cordifolia leaf extract as many as 50 mg/head weight (T2) orally.

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          Most cited references31

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          • Abstract: not found
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          Determining the stage of the estrous cycle in the mouse by the appearance of the vagina.

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            • Article: not found

            Antimicrobial activity, toxicity and the isolation of a bioactive compound from plants used to treat sexually transmitted diseases.

            Extracts of six ethnobotanically selected medicinal plants (Anredera cordifolia, Elaeodendron transvaalense, Elephantorrhiza burkei, Senna petersiana, Terminalia sericea and Rauvolfia caffra) used traditionally to treat sexually transmitted diseases (STD's) were investigated for antibacterial activity using the agar dilution method. Of the six collected, Terminalia sericea, Senna petersiana and Anredera cordifolia were also investigated for cytotoxicity. The phytochemical studies on Senna petersiana resulted in the isolation of luteolin, which also showed antimicrobial activity. Only the Senna petersiana extract and luteolin isolated from it were tested for antiviral activity and showed some activity at the highest non-toxic concentration of 24 and 500 microg/ml, respectively. The results of the antimicrobial screening support the ethnomedicinal uses of these plants to some extent.
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              • Article: not found

              Effective treatment of vaginal atrophy with isoflavone vaginal gel.

              To assess efficacy and tolerability of a isoflavone (Glycine max L. Merr.) vaginal gel to the treatment of vaginal atrophy in postmenopausal women.
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                Author and article information

                Journal
                Vet World
                Vet World
                Veterinary World
                Veterinary World (India )
                0972-8988
                2231-0916
                April 2017
                04 April 2017
                : 10
                : 4
                : 375-379
                Affiliations
                [1]Department of Animal Science, Faculty of Animal and Agricultural Sciences, Diponegoro University, Tembalang Campus, Semarang 50275, Central Java, Indonesia
                Author notes
                Article
                10.14202/vetworld.2017.375-379
                5422239
                a1ef4036-0816-48e9-8f6b-c23f5fc3ee5a
                Copyright: © Wijayanti, et al.

                Open Access. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License ( http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver ( http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

                History
                : 12 October 2016
                : 21 February 2017
                Categories
                Research Article

                anredera cordifolia,cavia cobaya,estrus cycle,postpartum

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