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      Natural Interferon Therapy: Optic Nerve Ischemic Damage?

      , , ,

      Ophthalmologica

      S. Karger AG

      Optic nerve, Interferon, Disk edema, Hepatitis C

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          Abstract

          The purpose of this study was the evaluation of retinal abnormalities during a treatment with natural interferon (IFN-α for chronic hepatitis C. Retinal hemorrhages and optic disk edema were found in a 40-year-old woman during IFN-α therapy. The disk edema and retinopathy resolved after the INF was discontinued. Although retinal abnormalities correlated with IFN therapy have been described recently by some authors, the pathogenesis is still unclear. Anterior ischemic optic neuropathy occurring in a patient treated with IFN is a probable complication of the therapy.

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          Author and article information

          Journal
          OPH
          Ophthalmologica
          10.1159/issn.0030-3755
          Ophthalmologica
          S. Karger AG
          0030-3755
          1423-0267
          1999
          October 1999
          24 September 1999
          : 213
          : 5
          : 339-340
          Affiliations
          Ophthalmic Clinic, IRCCS-Policlinico San Matteo, University of Pavia, Italy
          Article
          27450 Ophthalmologica 1999;213:339–340
          10.1159/000027450
          10516525
          © 1999 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          Page count
          Figures: 2, References: 8, Pages: 2
          Categories
          Case Report · Description de cas · Fallbericht

          Vision sciences, Ophthalmology & Optometry, Pathology

          Disk edema, Optic nerve, Hepatitis C, Interferon

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