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Safety and efficacy of oral nemonoxacin versus levofloxacin in treatment of community-acquired pneumonia: A phase 3, multicenter, randomized, double-blind, double-dummy, active-controlled, non-inferiority trial
Jinyi Yuan ,
Biwen Mo ,
Zhuang Ma ,
Yuan Lv ,
Shih-Lung Cheng ,
Yanping Yang ,
Zhaohui Tong ,
Renguang Wu ,
Shenghua Sun ,
Zhaolong Cao ,
Jufang Wu ,
Demei Zhu ,
Liwen Chang ,
Yingyuan Zhang ,
Li Zhao ,
Xiongbiao Wang ,
Xuefen Wang ,
Dexi Wang ,
Xiangyang Li ,
Yiqiang Peng ,
Yongjie Liang ,
Hua Liu ,
Zuke Xiao ,
Xiaoju Lv ,
Shiman Wu ,
Yuanrong Dai ,
Yijiang Huang ,
Zhenghong Hu ,
Chen Qiu ,
Xi Li ,
Suiyang Zhang ,
Wenpu Li ,
Shuang Liu ,
Yi Shi ,
Chang Xiong ,
Jiulong Kuang ,
Qingyu Xiu ,
Shehuai Cui ,
Jianguo Li ,
Qichang Lin ,
Wenxiang Huang ,
Yixin Wan ,
Qimanguli ,
Ce Shen ,
Yi Xiao ,
Xiaoju Wu ,
Yin Ching Chuang ,
Wann Cherng Perng ,
Shih-Ming Tsao ,
Jeng-Yuan Hsu ,
Chin-Chou Wang ,
Jen-Hsien Wang ,
Pen-Fang Yeh ,
His-Hsun Lin ,
P.H. Kuo ,
Ming-Shian Lin ,
Wei-Juin Su
August 2017
August 2017
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Abstract
<p class="first" id="d6576582e250">Nemonoxacin is a novel nonfluorinated quinolone
with excellent in vitro activity against
most pathogens in community-acquired pneumonia (CAP), especially Gram-positive isolates.
The purpose of this study was to assess the efficacy and safety of nemonoxacin compared
with levofloxacin in patients with CAP.
</p>