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      Influences of Sex, Education, and Country of Birth on Clinical Presentations and Overall Outcomes of Interdisciplinary Pain Rehabilitation in Chronic Pain Patients: A Cohort Study from the Swedish Quality Registry for Pain Rehabilitation (SQRP)

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          Abstract

          This study investigates the effects of sex, education, and country of birth on clinical presentations and outcomes of interdisciplinary multimodal pain rehabilitation programs (IMMRPs). A multivariate improvement score (MIS) and two retrospective estimations of changes in pain and ability to handle life situations were used as the three overall outcomes of IMMRPs. The study population consisted of chronic pain patients within specialist care in the Swedish Quality Registry for Pain Rehabilitation (SQRP) between 2008 and 2016 at baseline (n = 39,916), and for the subset participating in IMMRPs (n = 14,666). A cluster analysis based on sex, education, and country of origin revealed significant differences in the following aspects: best baseline clinical situation was for European women with university educations and the worst baseline clinical situation was for all patients born outside Europe of both sexes and different educations (i.e., moderate-large effect sizes). In addition, European women with university educations also had the most favorable overall outcomes in response to IMMRPs (small effect sizes). These results raise important questions concerning fairness and equality and need to be considered when optimizing assessments and content and delivery of IMMRPs for patients with chronic pain.

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          In September 2006, members of the Sex, Gender and Pain Special Interest Group of the International Association for the Study of Pain met to discuss the following: (1) what is known about sex and gender differences in pain and analgesia; (2) what are the "best practice" guidelines for pain research with respect to sex and gender; and (3) what are the crucial questions to address in the near future? The resulting consensus presented herein includes input from basic science, clinical and psychosocial pain researchers, as well as from recognized experts in sexual differentiation and reproductive endocrinology. We intend this document to serve as a utilitarian and thought-provoking guide for future research on sex and gender differences in pain and analgesia, both for those currently working in this field as well as those still wondering, "Do I really need to study females?"
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                Author and article information

                Journal
                J Clin Med
                J Clin Med
                jcm
                Journal of Clinical Medicine
                MDPI
                2077-0383
                25 July 2020
                August 2020
                : 9
                : 8
                : 2374
                Affiliations
                [1 ]Pain and Rehabilitation Centre, Department of Health, Medicine and Caring Sciences, Linköping University, SE-581 83 Linköping, Sweden; britt.larsson@ 123456liu.se
                [2 ]School of Law, Psychology and Social Work, Örebro University, SE-701 82 Örebro, Sweden; Katja.Boersma@ 123456oru.se
                [3 ]Department of Neuroscience, Uppsala University, SE-751 05 Uppsala, Sweden; pernilla.asenlof@ 123456neuro.uu.se
                [4 ]Department of Community Medicine and Rehabilitation, Rehabilitation Medicine, Umeå University, SE-901 87 Umeå, Sweden; britt-marie.stalnacke@ 123456umu.se
                [5 ]Department of Neurosurgery and Pain Rehabilitation, Skåne University Hospital, SE-221 85 Lund, Sweden; Asa.Ringqvist@ 123456skane.se
                Author notes
                [* ]Correspondence: bjorn.gerdle@ 123456liu.se ; Tel.: +46-763927191
                Author information
                https://orcid.org/0000-0002-4316-1264
                https://orcid.org/0000-0001-8605-2458
                Article
                jcm-09-02374
                10.3390/jcm9082374
                7466148
                32722367
                a22de6fe-e7f7-4cf7-b866-a6ceb3892b4e
                © 2020 by the authors.

                Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license ( http://creativecommons.org/licenses/by/4.0/).

                History
                : 02 June 2020
                : 23 July 2020
                Categories
                Article

                chronic pain,country of birth,education,sex,rehabilitation,interdisciplinary,outcome

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