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      Stabilized polymeric nanoparticles for controlled and efficient release of bifenthrin

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      Pest Management Science

      Wiley

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          Abstract

          Nanoparticle formulations of pesticides have been proposed to produce a better spatial distribution of the pesticide on leaf surfaces, which provides better efficiency. Nanoparticles are well studied for drug delivery and sustained release but not in the agricultural sciences, because of the difficulty in generating stable pesticide nanoparticles with controlled particle size distribution and because the processes to generate nanoparticles are usually costly. In this paper, a model pesticide, bifenthrin, has been prepared in nanoparticle form by using the Flash NanoPrecipitation process. The process involves rapid micromixing to effect supersaturation, and polymer assembly to control particle size.

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          Colloidal Dispersions

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            Organic Nanoparticles in the Aqueous Phase-Theory, Experiment, and Use.

             J. Rieger,  Susan Horn (2001)
            Many active organic compounds and organic effect materials are poorly soluble in water, or even insoluble. Aqueous forms of application thus require special formulation techniques to utilize or optimize the physiological (pharmaceuticals, cosmetics, plant protection, nutrition) or technical (varnishes, printing inks, toners) action. The most interesting properties of nanodispersions of active organic compounds and effect materials include the impressive increase in solubility, the improvement in biological resorption, and the modification of optical, electrooptical, and other physical properties which are achievable only with particle sizes in the middle or lower nanometer range (50-500 nm). Hence in addition to economic and ecological constraints there are also technical demands which appear to urgently require the development of new processes for the production of organic nanoparticles as alternatives to the established mechanical milling processes. In this context attention is drawn to the recent increase in research activities which have as their objective the continuous, automatic preparation of nanodispersed systems by precipitation from molecular solution. In this review the current state of knowledge of the fundamentals of particle formation from homogeneous solution and the effect of solvent and polymer additives on the morphology and supramolecular structure of the nanoparticle will be discussed. The practical implementation of this new formulation technology will be explored in detail for the carotenoids, a class of compounds of both physiological and technical interest.
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              Author and article information

              Journal
              PS
              Pest Management Science
              Pest. Manag. Sci.
              Wiley
              1526498X
              15264998
              August 2008
              August 2008
              : 64
              : 8
              : 808-812
              Article
              10.1002/ps.1566
              18366056
              © 2008

              http://doi.wiley.com/10.1002/tdm_license_1.1

              Product
              Self URI (article page): http://doi.wiley.com/10.1002/ps.1566

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