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      Pneumocystis carinii pneumonia in a patient on etanercept for psoriatic arthritis.

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      Publication date:
      Journal: Irish Journal of Medical Science
      Keywords: Adult, Arthritis, Psoriatic, drug therapy, immunology, Biopsy, Needle, Follow-Up Studies, Humans, Immunoglobulin G, adverse effects, therapeutic use, Immunohistochemistry, Immunosuppression, Immunosuppressive Agents, Male, Pneumonia, Pneumocystis, etiology, pathology, Receptors, Tumor Necrosis Factor, Risk Assessment, Severity of Illness Index, Treatment Outcome, Trimethoprim-Sulfamethoxazole Combination

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          Abstract

          Pneumocystis carinii pneumonia (PCP) is a rare form of pneumonia associated with immune-suppression. It is common in patients with AIDS and with a CD4 count of less than 200 cells/mm(3). We report a case of PCP secondary to immune-suppression in a 41-year-old man with psoriatic arthritis being treated with the immune-modulatory agent etanercept. Diagnosis of PCP was made histologically using tissue obtained via transbronchial biopsy. There was a good response to standard treatment with high-dose co-trimoxazole. This report highlights a recognised but previously unreported complication of etanercept.

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          PubMed ID:: 17906888
          DOI:: 10.1007/s11845-007-0087-x

          ScienceOpen disciplines: Chemistry
          Keywords: Adult,Arthritis, Psoriatic,drug therapy,immunology,Biopsy, Needle,Follow-Up Studies,Humans,Immunoglobulin G,adverse effects,therapeutic use,Immunohistochemistry,Immunosuppression,Immunosuppressive Agents,Male,Pneumonia, Pneumocystis,etiology,pathology,Receptors, Tumor Necrosis Factor,Risk Assessment,Severity of Illness Index,Treatment Outcome,Trimethoprim-Sulfamethoxazole Combination
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          ScienceOpen disciplines: Chemistry
          Keywords: Adult, Arthritis, Psoriatic, drug therapy, immunology, Biopsy, Needle, Follow-Up Studies, Humans, Immunoglobulin G, adverse effects, therapeutic use, Immunohistochemistry, Immunosuppression, Immunosuppressive Agents, Male, Pneumonia, Pneumocystis, etiology, pathology, Receptors, Tumor Necrosis Factor, Risk Assessment, Severity of Illness Index, Treatment Outcome, Trimethoprim-Sulfamethoxazole Combination

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