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      Prevalence of Heart Disease in Asymptomatic Chronic Cocaine Users

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          To determine the prevalence of heart disease in outpatient young asymptomatic chronic cocaine users, 35 cocaine users and 32 age-matched controls underwent resting and exercise electrocardiography (ECG) and Doppler echocardiography. Findings consistent with coronary artery disease were detected in 12 (34%) patients and 3 (9%) controls (p = 0.01). Decreased left ventricular systolic function was demonstrated in 5 (14%) patients, but in none of the controls (p = 0.055). Finally, resting and peak exercise abnormal left ventricular filling was detected in 38 and 35% of patients as compared to 19 and 9% of controls, respectively (p = 0.11 and 0.02, respectively). We conclude that coronary artery or myocardial disease is common (38%) in young asymptomatic chronic cocaine users. Therefore, screening ECG and echocardiography may be warranted in these patients.

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          Author and article information

          S. Karger AG
          May 2001
          25 May 2001
          : 95
          : 1
          : 25-30
          Veterans Affairs Medical Center and University of New Mexico Health Sciences Center, Albuquerque, N.Mex., USA
          47339 Cardiology 2001;95:25–30
          © 2001 S. Karger AG, Basel

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          Page count
          Tables: 4, References: 19, Pages: 6
          General Cardiology


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