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      Catalytic Enantioselective CH Functionalization of Alcohols by Redox-Triggered Carbonyl Addition: Borrowing Hydrogen, Returning Carbon

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      Angewandte Chemie International Edition
      Wiley-Blackwell

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          Analysis of the reactions used for the preparation of drug candidate molecules.

          The purpose of this perspective is to indicate the range of chemistries used in the manufacture of drug candidate molecules and to highlight certain gaps in current technologies. To do this a survey was carried out of chemical syntheses within the Process Chemistry R&D departments of GlaxoSmithKline, AstraZeneca and Pfizer.
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            Borrowing Hydrogen in the Activation of Alcohols

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              586. Olefin co-ordination compounds. Part III. Infra-red spectra and structure: attempted preparation of acetylene complexes

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                Author and article information

                Journal
                Angewandte Chemie International Edition
                Angew. Chem. Int. Ed.
                Wiley-Blackwell
                14337851
                August 25 2014
                August 25 2014
                : 53
                : 35
                : 9142-9150
                Article
                10.1002/anie.201403873
                a2cb3287-f3df-45b6-aca2-8c481f17ec29
                © 2014

                http://doi.wiley.com/10.1002/tdm_license_1.1

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