3
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: not found
      • Article: not found

      Imaging of spatiotemporal coincident states by DC optical tomography

      , ,
      IEEE Transactions on Medical Imaging
      Institute of Electrical and Electronics Engineers (IEEE)

      Read this article at

      ScienceOpenPublisher
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Related collections

          Most cited references31

          • Record: found
          • Abstract: not found
          • Book: not found

          Applied Nonlinear Dynamics

            Bookmark
            • Record: found
            • Abstract: found
            • Article: not found

            Quantitative hemoglobin tomography with diffuse near-infrared spectroscopy: pilot results in the breast.

            The authors describe what is, to the best of their knowledge, the first quantitative hemoglobin concentration images of the female breast that were formed with model-based reconstruction of near-infrared intensity-modulated tomographic data. The results in 11 patients, including two with breast tumors with pathologic correlation, are summarized. Hemoglobin concentration appears to correlate with tumor vascularity without the need for exogenous contrast material and thereby has intrinsic diagnostic value.
              Bookmark
              • Record: found
              • Abstract: found
              • Article: not found

              Near-infrared spectroscopy: does it function in functional activation studies of the adult brain?

              Changes in optical properties of biological tissue can be examined by near-infrared spectroscopy (NIRS). The relative transparency of tissues including the skull to near-infrared light is the prerequisite to apply the method to brain research. We describe the methodology with respect to its applicability in non-invasive functional research of the adult cortex. A summary of studies establishing the 'typical' response in NIRS vascular parameters, i.e. changes in the concentration of oxygenated and deoxygenated haemoglobin, over an activated area is followed by the validation of changes in the cytochrome-oxidase redox state in response to a visual stimulus. Proceeding from these findings a rough mapping of this metabolic response over the motion-sensitive extrastriate visual area is demonstrated. NIRS measures concentration changes in deoxygenated haemoglobin [deoxy-Hb] which are assumed to be the basis of fMRI BOLD contrast (blood oxygenation level-dependent). The method is therefore an excellent tool to validate assumptions on the physiological basis underlying the fMRI signal, due to its high specificity as to the parameters measured. Questions concerning the concept of 'activation'/'deactivation' and that of the linearity of the vascular response are discussed. To challenge the method we finally present results from a complex single-trial motor paradigm study testing the hypothesis, that premotor potentials (contingent negative variation) can be examined by functional techniques relying on the vascular response. Some of the work described here has been published elsewhere.
                Bookmark

                Author and article information

                Journal
                IEEE Transactions on Medical Imaging
                IEEE Trans. Med. Imaging
                Institute of Electrical and Electronics Engineers (IEEE)
                0278-0062
                August 2002
                August 2002
                : 21
                : 8
                : 852-866
                Article
                10.1109/TMI.2002.801154
                a30e1a64-edda-4bc4-a50f-8470254837dd
                © 2002
                History

                Comments

                Comment on this article