1
views
0
recommends
+1 Recommend
1 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Hyperthyroidism as a Precipitant Factor for Cerebral Venous Thrombosis: A Case Report

      case-report

      Read this article at

      ScienceOpenPublisherPMC
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Cerebral venous sinus thrombosis (CVT) is an uncommon yet serious condition. While CVT has many known precipitants and etiologies, hyperthyroidism as a precipitant of CVT is not well understood. This study reported a case of a 41-year-old male with a 4-year history of hyperthyroidism presented with seizure. Consequently, a diagnosis of superior sagittal sinus thrombosis was confirmed by computed tomography and magnetic resonance (MR) venograms. Extensive investigations yielded no apparent underlying cause, but laboratory findings were consistent with uncontrolled hyperthyroidism. The patient improved rapidly following anticoagulation. Follow-up MR and MRV scans 2 months after treatment revealed full recanalization of the superior sagittal sinus. This case report highlighted hyperthyroidism, as a procoagulant condition, resulting specifically in superior sagittal sinus thrombosis.

          Related collections

          Most cited references19

          • Record: found
          • Abstract: not found
          • Article: not found

          Clinical practice. Graves' disease.

            Bookmark
            • Record: found
            • Abstract: found
            • Article: not found

            The incidence of cerebral venous thrombosis: a cross-sectional study.

            The purpose of this study was to determine the incidence of adult cerebral venous thrombosis.
              Bookmark
              • Record: found
              • Abstract: found
              • Article: not found

              Cerebral venous and sinus thrombosis in women.

              Little is known about the gender-specific manifestations of cerebral venous and sinus thrombosis, a disease that is much more common in women than men. We used data of the International Study on Cerebral Vein and Dural sinus Thrombosis (ISCVT), a multicenter prospective observational study, to analyze gender-specific differences in clinical presentation, etiology, and outcome of cerebral venous thrombosis. Four hundred sixty-five of a total of 624 patients were women (75%). Women were significantly younger, had less often a chronic onset of symptoms, and had more often headache at presentation. There were no gender differences in ancillary investigations or treatment. A gender-specific risk factor (oral contraceptives, pregnancy, puerperium, and hormonal replacement therapy) was present in 65% of women. Women had a better prognosis than men (complete recovery 81% versus 71%l P=0.01), which was entirely due to a better outcome in female patients with gender-specific risk factors. Women without gender-specific risk factors are similar to men in clinical presentation, risk factor profile, and outcome. Logistic regression analysis confirmed that the absence of gender-specific risk factors is a strong and independent predictor of poor outcome in women with sinus thrombosis (OR, 3.7; CI, 1.9 to 7.4). Our study identified important differences between women and men in presentation, course, and risk factors of cerebral venous and sinus thrombosis and showed that women with a gender-specific risk factor have a much better prognosis than other patients.
                Bookmark

                Author and article information

                Journal
                J Investig Med High Impact Case Rep
                J Investig Med High Impact Case Rep
                HIC
                sphic
                Journal of Investigative Medicine High Impact Case Reports
                SAGE Publications (Sage CA: Los Angeles, CA )
                2324-7096
                12 August 2020
                Jan-Dec 2020
                : 8
                : 2324709620949309
                Affiliations
                [1 ]University of Khartoum, Khartoum, Sudan
                [2 ]Hamad Medical Corporation, Doha, Qatar
                Author notes
                [*]Ahmed Elkhalifa Elawad Elhassan, University of Khartoum, Al Qasr Street, Khartoum 11111, Sudan. Email: ahmed-khalifa@ 123456live.com
                Author information
                https://orcid.org/0000-0002-3651-4885
                https://orcid.org/0000-0002-5815-9466
                Article
                10.1177_2324709620949309
                10.1177/2324709620949309
                7427011
                32787455
                a328c64c-b3f8-4436-ab51-8a71959dec9c
                © 2020 American Federation for Medical Research

                This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License ( https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages ( https://us.sagepub.com/en-us/nam/open-access-at-sage).

                History
                : 24 June 2020
                : 17 July 2020
                : 18 July 2020
                Categories
                Case Report
                Custom metadata
                January-December 2020
                ts1

                cerebral venous sinus thrombosis,cvt,superior sagittal sinus thrombosis,hyperthyroidism,hypercoagulable state

                Comments

                Comment on this article