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Abstract
<p class="first" id="d5030012e80">Frailty is a clinical state characterized by a decrease
of an individual's homeostatic
reserves and is responsible for enhanced vulnerability to endogenous and/or exogenous
stressors. Such a condition of extreme vulnerability exposes individuals to an increased
risk of negative health-related outcomes. Multiple operational definitions of frailty
are available in the literature, but none can be indicated as a gold standard. Frailty
should be considered a condition of major interest for public health and become the
lever for reshaping the obsolete health care systems currently unable to adequately
address the clinical needs of aging populations.
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