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      Central Nervous System Involvement in Thrombotic Thrombocytopenic Purpura

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          Abstract

          Thrombotic thrombocytopenic purpura (TTP) is an uncommon multisystem disease characterized by microangiopathic hemolytic anemia, thrombocytopenic purpura, fluctuating neurologic dysfunctions, renal disease, and fever. Delayed diagnosis and treatment may lead to a high mortality rate that can be as great as 90%. We describe 7 patients in whom CNS involvement was the first clinical manifestation of TTP. Despite early diagnosis and treatment, 3 patients died because of multiple system organ failure. Four patients recovered completely. In patients with focal neurologic disorders in whom infectious CNS diseases were excluded TTP should be considered in the differential diagnosis.

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          Most cited references 3

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          Thrombotic thrombocytopenic purpura related to ticlopidine

           Y Page,  F Zeni,  B Tardy (1991)
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            Microangiopathic hemolysis and thrombocytopenia related to penicillin drugs

             J. PARKER (1971)
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              • Record: found
              • Abstract: not found
              • Article: not found

              Thrombohemolytic thrombocytopenic purpura during penicillamine therapy

               F. AHMED (1978)
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                Author and article information

                Journal
                ENE
                Eur Neurol
                10.1159/issn.0014-3022
                European Neurology
                S. Karger AG
                0014-3022
                1421-9913
                1998
                November 1998
                20 November 1998
                : 40
                : 4
                : 220-224
                Affiliations
                Departments of a Neurology and Internal Medicine b I and c III, University of Erlangen-Nuremberg, Erlangen, Germany
                Article
                7983 Eur Neurol 1998;40:220–224
                10.1159/000007983
                9813405
                © 1998 S. Karger AG, Basel

                Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

                Page count
                Figures: 2, Tables: 1, References: 29, Pages: 5
                Categories
                Original Paper

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