Kate Jolly 1 , Saimma Majothi 1 , Alice J Sitch 1 , Nicola R Heneghan 2 , Richard D Riley 3 , David J Moore 1 , Elizabeth J Bates 1 , Alice M Turner 4 , Susan E Bayliss 1 , Malcolm J Price 1 , Sally J Singh 5 , Peymane Adab 1 , David A Fitzmaurice 1 , Rachel E Jordan 1
17 February 2016
This systematic review aimed to identify the most effective components of interventions to facilitate self-management of health care behaviors for patients with COPD. PROSPERO registration number CRD42011001588.
We used standard review methods with a systematic search to May 2012 for randomized controlled trials of self-management interventions reporting hospital admissions or health-related quality of life (HRQoL). Mean differences (MD), hazard ratios, and 95% confidence intervals (CIs) were calculated and pooled using random-effects meta-analyses. Effects among different subgroups of interventions were explored including single/multiple components and multicomponent interventions with/without exercise.
One hundred and seventy-three randomized controlled trials were identified. Self-management interventions had a minimal effect on hospital admission rates. Multicomponent interventions improved HRQoL (studies with follow-up >6 months St George’s Respiratory Questionnaire (MD 2.40, 95% CI 0.75–4.04, I 2 57.9). Exercise was an effective individual component (St George’s Respiratory Questionnaire at 3 months MD 4.87, 95% CI 3.96–5.79, I 2 0%).