7
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: not found

      Preparation and characterization of poly(triallyl isocyanurate-co-trimethylolpropane triacrylate) monolith and its applications in the separation of small molecules by liquid chromatography.

      Read this article at

      ScienceOpenPublisherPubMed
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          A new polymeric monolith was prepared in stainless-steel column and fused-silica capillary, respectively, by atom transfer radical polymerization technique. In the polymerization, triallyl isocyanurate (TAIC) was used as the functional monomer; trimethylolpropane triacrylate (TMPTA) as the crosslinking agent; polyethylene glycol 200 and 1,2-propanediol as the co-porogens; carbon tetrachloride as the initiator and ferrous chloride as the catalyst. The conditions of polymerization were optimized. Morphology of the prepared poly(TAIC-co-TMPTA) monolith was investigated by scanning electron microscopy; pore properties were assayed by mercury porosimetry and nitrogen adsorption. The characterization indicated that the prepared reversed-phase monolith possessed uniform structure, good permeability and mechanical stability. The column was used as the stationary phase of reversed phase high performance liquid chromatography (RP-HPLC) and capillary liquid chromatography (CLC) to separate the mixture of aromatic compounds. The new column performed around 125,000 theoretical plates per meter. The column showed good reproducibility: the relative standard deviation values of the retention factor values for aromatic compounds were less than 1.52% (n=7, column-to-column).

          Related collections

          Author and article information

          Journal
          J Chromatogr A
          Journal of chromatography. A
          Elsevier BV
          1873-3778
          0021-9673
          Mar 14 2014
          : 1333
          Affiliations
          [1 ] Key Laboratory of Pharmaceutical Quality Control of Hebei Province, Baoding 071002, China; College of Pharmaceutical Sciences, Hebei University, Baoding 071002, China.
          [2 ] Key Laboratory of Pharmaceutical Quality Control of Hebei Province, Baoding 071002, China; College of Pharmaceutical Sciences, Hebei University, Baoding 071002, China. Electronic address: ygl@hbu.edu.cn.
          Article
          S0021-9673(14)00167-8
          10.1016/j.chroma.2014.01.072
          24556171
          a3c8e02c-c595-4b80-8f6b-31a949d511d1
          Copyright © 2014 Elsevier B.V. All rights reserved.

          Capillary liquid chromatography (CLC),High performance liquid chromatography (HPLC),Poly(TAIC-co-TMPTA) monolith,Reversed-phase chromatography,Small molecules

          Comments

          Comment on this article