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      Integration of Global and Local Features for Specular Reflection Inpainting in Colposcopic Images

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          Abstract

          Objective

          To explore an inpainting method that can balance texture details and visual observability to eliminate the specular reflection (SR) regions in the colposcopic image, thus improving the accuracy of clinical diagnosis for cervical cancer.

          Methods

          (1) To ensure smoothness, Gaussian Blur and filling methods are applied to the global image. (2) Striving to preserve the anatomical texture details of the colposcopic image as much as possible, the exemplar-based method is applied to local blocks. (3) The colposcopic images inpainted in the previous two steps are integrated, so that important information of non-SR regions is preserved based on eliminating SR regions.

          Results

          In the subjective visual assessment of inpainting results, the average of 3.55 ranks first in the five comparison sets. As to the clinical test, comparing the diagnosis results of 6 physicians before and after eliminating SR regions, the average accuracy of two kinds of classifications increased by 1.44% and 2.03%, respectively.

          Conclusions

          This method can effectively eliminate the SR regions in the colposcopy image and present a satisfactory visual effect. Significance. As a preprocessing method for computer-aided diagnosis systems, it can also improve physicians' accuracy in clinical diagnosis.

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          Most cited references40

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          Global Cancer Statistics 2018: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries

          This article provides a status report on the global burden of cancer worldwide using the GLOBOCAN 2018 estimates of cancer incidence and mortality produced by the International Agency for Research on Cancer, with a focus on geographic variability across 20 world regions. There will be an estimated 18.1 million new cancer cases (17.0 million excluding nonmelanoma skin cancer) and 9.6 million cancer deaths (9.5 million excluding nonmelanoma skin cancer) in 2018. In both sexes combined, lung cancer is the most commonly diagnosed cancer (11.6% of the total cases) and the leading cause of cancer death (18.4% of the total cancer deaths), closely followed by female breast cancer (11.6%), prostate cancer (7.1%), and colorectal cancer (6.1%) for incidence and colorectal cancer (9.2%), stomach cancer (8.2%), and liver cancer (8.2%) for mortality. Lung cancer is the most frequent cancer and the leading cause of cancer death among males, followed by prostate and colorectal cancer (for incidence) and liver and stomach cancer (for mortality). Among females, breast cancer is the most commonly diagnosed cancer and the leading cause of cancer death, followed by colorectal and lung cancer (for incidence), and vice versa (for mortality); cervical cancer ranks fourth for both incidence and mortality. The most frequently diagnosed cancer and the leading cause of cancer death, however, substantially vary across countries and within each country depending on the degree of economic development and associated social and life style factors. It is noteworthy that high-quality cancer registry data, the basis for planning and implementing evidence-based cancer control programs, are not available in most low- and middle-income countries. The Global Initiative for Cancer Registry Development is an international partnership that supports better estimation, as well as the collection and use of local data, to prioritize and evaluate national cancer control efforts. CA: A Cancer Journal for Clinicians 2018;0:1-31. © 2018 American Cancer Society.
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            Cancer statistics, 2020

            Each year, the American Cancer Society estimates the numbers of new cancer cases and deaths that will occur in the United States and compiles the most recent data on population-based cancer occurrence. Incidence data (through 2016) were collected by the Surveillance, Epidemiology, and End Results Program; the National Program of Cancer Registries; and the North American Association of Central Cancer Registries. Mortality data (through 2017) were collected by the National Center for Health Statistics. In 2020, 1,806,590 new cancer cases and 606,520 cancer deaths are projected to occur in the United States. The cancer death rate rose until 1991, then fell continuously through 2017, resulting in an overall decline of 29% that translates into an estimated 2.9 million fewer cancer deaths than would have occurred if peak rates had persisted. This progress is driven by long-term declines in death rates for the 4 leading cancers (lung, colorectal, breast, prostate); however, over the past decade (2008-2017), reductions slowed for female breast and colorectal cancers, and halted for prostate cancer. In contrast, declines accelerated for lung cancer, from 3% annually during 2008 through 2013 to 5% during 2013 through 2017 in men and from 2% to almost 4% in women, spurring the largest ever single-year drop in overall cancer mortality of 2.2% from 2016 to 2017. Yet lung cancer still caused more deaths in 2017 than breast, prostate, colorectal, and brain cancers combined. Recent mortality declines were also dramatic for melanoma of the skin in the wake of US Food and Drug Administration approval of new therapies for metastatic disease, escalating to 7% annually during 2013 through 2017 from 1% during 2006 through 2010 in men and women aged 50 to 64 years and from 2% to 3% in those aged 20 to 49 years; annual declines of 5% to 6% in individuals aged 65 years and older are particularly striking because rates in this age group were increasing prior to 2013. It is also notable that long-term rapid increases in liver cancer mortality have attenuated in women and stabilized in men. In summary, slowing momentum for some cancers amenable to early detection is juxtaposed with notable gains for other common cancers.
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              Region Filling and Object Removal by Exemplar-Based Image Inpainting

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                Author and article information

                Contributors
                Journal
                J Healthc Eng
                J Healthc Eng
                JHE
                Journal of Healthcare Engineering
                Hindawi
                2040-2295
                2040-2309
                2021
                27 July 2021
                : 2021
                : 5401308
                Affiliations
                1College of Medicine, Huaqiao University, Quanzhou, Fujian 362021, China
                2Department of Gynecology and Obstetrics, The First Hospital of Quanzhou, Quanzhou, Fujian 362000, China
                3Cervical Disease Diagnosis and Treatment Health Center, Fujian Provincial Maternity and Children's Hospital, Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian 350001, China
                4College of Engineering, Huaqiao University, Quanzhou, Fujian 362021, China
                Author notes

                Academic Editor: Ayush Dogra

                Author information
                https://orcid.org/0000-0002-7131-1792
                https://orcid.org/0000-0003-0759-6866
                https://orcid.org/0000-0003-4261-9648
                https://orcid.org/0000-0003-2619-1629
                Article
                10.1155/2021/5401308
                8337142
                34367538
                a3ff9141-2bba-4f81-89b0-cc0e90b9196c
                Copyright © 2021 Xiaoxia Wang et al.

                This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                : 12 May 2021
                : 20 July 2021
                Funding
                Funded by: Quanzhou Scientific and Technological Planning Projects
                Award ID: 2019C028R
                Funded by: Fujian Provincial Department of Science and Technology
                Award ID: 2020HZ02014
                Categories
                Research Article

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