Blog
About

114
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: not found

      Heterogeneities in the transmission of infectious agents: implications for the design of control programs.

      Proceedings of the National Academy of Sciences of the United States of America

      transmission, Animals, Communicable Disease Control, Disease Transmission, Infectious, Disease Vectors, HIV Infections, prevention & control, Health Planning, Humans, Leishmaniasis, Malaria, Models, Theoretical, Schistosomiasis

      Read this article at

      ScienceOpenPMC
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          From an analysis of the distributions of measures of transmission rates among hosts, we identify an empirical relationship suggesting that, typically, 20% of the host population contributes at least 80% of the net transmission potential, as measured by the basic reproduction number, R0. This is an example of a statistical pattern known as the 20/80 rule. The rule applies to a variety of disease systems, including vector-borne parasites and sexually transmitted pathogens. The rule implies that control programs targeted at the "core" 20% group are potentially highly effective and, conversely, that programs that fail to reach all of this group will be much less effective than expected in reducing levels of infection in the population as a whole.

          Related collections

          Author and article information

          Journal
          19338
          8990210

          Comments

          Comment on this article