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      Postexercise Systolic Time Intervals in the Midsystolic Click Syndrome

      ,

      Cardiology

      S. Karger AG

      Exercise testing, Mitral valve prolapse, Systolic time intervals

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          Abstract

          Postexercise systolic time intervals (STI) were measured in ten patients (PMV group) with auscultatory evidence of the midsystolic click syndrome (i.e. one or more systolic nonejection clicks alone or in association with a late systolic murmur), and compared to eight age-matched volunteers (control group) with no evidence of heart disease. Following measurement of supine STIs, the subjects pedalled an upright bicycle ergometer at progressive work loads until a target heart rate (HR) representing 85% of the age-adjusted maximum was attained, or an abnormal end point was noted. Immediately postexercise, a repeat measurement of STIs, was obtained. A shortened or unchanged postexercise left ventricular ejection time corrected for HR (ΔLVETc) and a marked shortening of total electromechanical systole after exercise (ΔQS2c) constituted a normal STI response to stress testing and was noted in all control subjects. All of the PMV group exhibited evidence of left ventricular dysfunction characterized by a prolonged ΔLVETc. It is concluded that an abnormal STI response to exercise consistent with left ventricular dysfunction can be demonstrated in patients with prolapse of the mitral valve by the response of the STI.

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          Author and article information

          Journal
          CRD
          Cardiology
          10.1159/issn.0008-6312
          Cardiology
          S. Karger AG
          0008-6312
          1421-9751
          1977
          1977
          29 October 2008
          : 62
          : 1
          : 44-50
          Affiliations
          Division of Cardiology, University Hospital of Jacksonville, University of Florida College of Medicine, Jacksonville, Fla. and Cardiovascular Laboratory, Cleveland Metropolitan General Hospital, Case Western Reserve University School of Medicine, Cleveland, Ohio
          Article
          169838 Cardiology 1977;62:44–50
          10.1159/000169838
          872154
          © 1977 S. Karger AG, Basel

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          Page count
          Pages: 7
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