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      Time series modeling of pneumonia admissions and its association with air pollution and climate variables in Chiang Mai Province, Thailand

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          Abstract

          This study aimed to predict the number of pneumonia cases in Chiang Mai Province. An autoregressive integrated moving average (ARIMA) was used in data fitting and to predict future pneumonia cases monthly. Total pneumonia cases of 67,583 were recorded in Chiang Mai during 2003–2014 that the monthly pattern of case was similar every year. Monthly pneumonia cases were increased during February and September, which are the periods of winter and rainy season in Thailand and decreased during April to July (the period of summer season to early rainy season). Using available data on 12 years of pneumonia cases, air pollution, and climate in Chiang Mai, the optimum ARIMA model was investigated based on several conditions. Seasonal change was included in the models due to statistically strong season conditions. Twelve ARIMA model (ARMODEL1–ARMODEL12) scenarios were investigated. Results showed that the most appropriate model was ARIMA (1,0,2)(2,0,0)[12] with PM10 (ARMODEL5) exhibiting the lowest AIC of − 38.29. The predicted number of monthly pneumonia cases by using ARMODEL5 during January to March 2013 was 727, 707, and 658 cases, while the real number was 804, 868, and 783 cases, respectively. This finding indicated that PM 10 held the most important role to predict monthly pneumonia cases in Chiang Mai, and the model was able to predict future pneumonia cases in Chiang Mai accurately.

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          Most cited references23

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          The effect of ozone and PM10 on hospital admissions for pneumonia and chronic obstructive pulmonary disease: a national multicity study.

          A case-crossover study was conducted in 36 US cities to evaluate the effect of ozone and particulate matter with an aerodynamic diameter of < or =10 microm (PM10) on respiratory hospital admissions and to identify which city characteristics may explain the heterogeneity in risk estimates. Respiratory hospital admissions and air pollution data were obtained for 1986-1999. In a meta-analysis based on the city-specific regression models, several city characteristics were evaluated as effect modifiers. During the warm season, the 2-day cumulative effect of a 5-ppb increase in ozone was a 0.27% (95% confidence interval (CI): 0.08, 0.47) increase in chronic obstructive pulmonary disease admissions and a 0.41% (95% CI: 0.26, 0.57) increase in pneumonia admissions. Similarly, a 10-microg/m(3) increase in PM10 during the warm season resulted in a 1.47% (95% CI: 0.93, 2.01) increase in chronic obstructive pulmonary disease at lag 1 and a 0.84% (95% CI: 0.50, 1.19) increase in pneumonia at lag 0. Percentage of households with central air conditioning reduced the effect of air pollution, and variability of summer apparent temperature reduced the effect of ozone on chronic obstructive pulmonary disease. The study confirmed, in a large sample of cities, that exposure to ozone and PM10 is associated with respiratory hospital admissions and provided evidence that the effect of air pollution is modified by certain city characteristics.
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            Time series analysis of dengue incidence in Rio de Janeiro, Brazil.

            We use the Box-Jenkins approach to fit an autoregressive integrated moving average (ARIMA) model to dengue incidence in Rio de Janeiro, Brazil, from 1997 to 2004. We find that the number of dengue cases in a month can be estimated by the number of dengue cases occurring one, two, and twelve months prior. We use our fitted model to predict dengue incidence for the year 2005 when two alternative approaches are used: 12-steps ahead versus 1-step ahead. Our calculations show that the 1-step ahead approach for predicting dengue incidence provides significantly more accurate predictions (P value=0.002, Wilcoxon signed-ranks test) than the 12-steps ahead approach. We also explore the predictive power of alternative ARIMA models incorporating climate variables as external regressors. Our findings indicate that ARIMA models are useful tools for monitoring dengue incidence in Rio de Janeiro. Furthermore, these models can be applied to surveillance data for predicting trends in dengue incidence.
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              Air pollution and emergency admissions in Boston, MA.

              Many studies have shown that ambient particulate air pollution (PM) is associated with increased risk of hospital admissions and deaths for cardiovascular or respiratory causes around the world. In general these have been analysed in association with PM(10) and ozone, whereas PM(2.5) is now the particle measure of greatest health and regulatory concern. And little has been published on associations of hospital admissions and PM components. This study analysed hospital admissions for myocardial infarction (15 578 patients), and pneumonia (24 857 patients) in associations with fine particulate air pollution, black carbon (BC), ozone, nitrogen dioxide (NO(2)), PM not from traffic, and carbon monoxide (CO) in the greater Boston area for the years 1995-1999 using a case-crossover analysis, with control days matched on temperature. A significant association was found between NO(2) (12.7% change (95% CI: 5.8, 18)), PM(2.5) (8.6% increase (95% CI: 1.2, 15.4)), and BC (8.3% increase (95% CI: 0.2, 15.8)) and the risk of emergency myocardial infarction hospitalisation; and between BC (11.7% increase (95% CI: 4.8, 17.4)), PM(2.5) (6.5% increase (95% CI: 1.1, 11.4)), and CO (5.5% increase (95% CI: 1.1, 9.5)) and the risk of pneumonia hospitalisation. The pattern of associations seen for myocardial infarction and pneumonia (strongest associations with NO(2), CO, and BC) suggests that traffic exposure is primarily responsible for the association with heart attacks.
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                Author and article information

                Contributors
                +6623549100-4 , kraichat.tan@mahidol.ac.th
                Journal
                Environ Sci Pollut Res Int
                Environ Sci Pollut Res Int
                Environmental Science and Pollution Research International
                Springer Berlin Heidelberg (Berlin/Heidelberg )
                0944-1344
                1614-7499
                26 September 2018
                26 September 2018
                2018
                : 25
                : 33
                : 33277-33285
                Affiliations
                ISNI 0000 0004 1937 0490, GRID grid.10223.32, Department of Social and Environmental Medicine, Faculty of Tropical Medicine, , Mahidol University, ; Bangkok, Thailand
                Author notes

                Responsible editor: Philippe Garrigues

                Article
                3284
                10.1007/s11356-018-3284-4
                6245022
                30255274
                a4a1860b-90f0-4321-bad8-63983d02b1dd
                © The Author(s) 2018

                Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

                History
                : 14 February 2018
                : 18 September 2018
                Funding
                Funded by: Postdoctoral Fellowship Program, Mahidol University
                Categories
                Research Article
                Custom metadata
                © Springer-Verlag GmbH Germany, part of Springer Nature 2018

                General environmental science
                pneumonia,arima,arimax,pm10,climate change,air pollution,respiratory disease
                General environmental science
                pneumonia, arima, arimax, pm10, climate change, air pollution, respiratory disease

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