High seroprevalence of chikungunya virus antibodies among pregnant women living in an urban area in Benin, West Africa.

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Abstract

The aim of this study was to investigate the seroprevalence of antichikungunya virus (anti-CHIKV) antibodies in pregnant women living in an urban area of Benin (West Africa). Results were obtained by screening sera collected in 2006 and 2007 with enzyme-linked immunosorbent assay (ELISA) for anti-CHIKV immunoglobulin G (IgG) and IgM. Positive results were confirmed by indirect immunofluorescence test and microneutralization assay. We found that a large proportion (36.1%) of pregnant women living in Cotonou had specific IgG against CHIKV, indicating a high seroprevalence of the infection in urban southern Benin, whereas no active cases of CHIKV infection were detected.

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Journal

Journal ID (iso-abbrev): Am. J. Trop. Med. Hyg.

Title: The American journal of tropical medicine and hygiene

Publisher: American Society of Tropical Medicine and Hygiene

ISSN (Electronic): 1476-1645

ISSN (Print): 0002-9637

Publication date (Electronic): Jun 2015

Volume: 92

Issue: 6

Affiliations

[1 ] Unit of Clinical Microbiology, Regional Reference Centre for Microbiological Emergencies (CRREM), St. Orsola-Malpighi University Hospital, Bologna, Italy; Centre d'étude et de Recherche sur le Paludisme Associé à la Grossesse et à l'Enfance (CERPAGE), Faculté des Sciences de la Santé, Université d'Abomey-Calavi, Benin; Institut de Recherche pour le Développement, Unitès mixtes de Recherche (UMR) 216, Mère et Enfant Face aux Infections Tropicales, France; Pres Sorbonne Paris Cité, Université Paris Descartes, Faculté de Pharmacie, Paris, France; Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Bologna, Italy; Unit of Microbiology, Area Vasta Romagna (AVR), Pievesestina, Cesena, Italy.

[2 ] Unit of Clinical Microbiology, Regional Reference Centre for Microbiological Emergencies (CRREM), St. Orsola-Malpighi University Hospital, Bologna, Italy; Centre d'étude et de Recherche sur le Paludisme Associé à la Grossesse et à l'Enfance (CERPAGE), Faculté des Sciences de la Santé, Université d'Abomey-Calavi, Benin; Institut de Recherche pour le Développement, Unitès mixtes de Recherche (UMR) 216, Mère et Enfant Face aux Infections Tropicales, France; Pres Sorbonne Paris Cité, Université Paris Descartes, Faculté de Pharmacie, Paris, France; Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Bologna, Italy; Unit of Microbiology, Area Vasta Romagna (AVR), Pievesestina, Cesena, Italy giada.rossini@unibo.it.

Article

Publisher Item ID: ajtmh.14-0092

DOI: 10.4269/ajtmh.14-0092

PMC ID: 4458815

PubMed ID: 25940198

SO-VID: a4d9e2d2-251e-4d1c-8738-38b67664ca68

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