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      Interval estimation for the difference between independent proportions: comparison of eleven methods

      Statistics in Medicine
      Wiley

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          Abstract

          Several existing unconditional methods for setting confidence intervals for the difference between binomial proportions are evaluated. Computationally simpler methods are prone to a variety of aberrations and poor coverage properties. The closely interrelated methods of Mee and Miettinen and Nurminen perform well but require a computer program. Two new approaches which also avoid aberrations are developed and evaluated. A tail area profile likelihood based method produces the best coverage properties, but is difficult to calculate for large denominators. A method combining Wilson score intervals for the two proportions to be compared also performs well, and is readily implemented irrespective of sample size.

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          Author and article information

          Journal
          Statistics in Medicine
          Statist. Med.
          Wiley
          0277-6715
          1097-0258
          April 30 1998
          April 30 1998
          : 17
          : 8
          : 873-890
          Article
          10.1002/(SICI)1097-0258(19980430)17:8<873::AID-SIM779>3.0.CO;2-I
          9595617
          a4e6e9a1-c9a0-4d2f-888a-69c5931fa55c
          © 1998

          http://doi.wiley.com/10.1002/tdm_license_1.1

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