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      Disease Labels and Clear Communication With Patients—A Rose by Any Other Name Would Smell as Sweet

      1 , 1
      JAMA Oncology
      American Medical Association (AMA)

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          Controversies in the Treatment of Ductal Carcinoma in Situ

          Ductal carcinoma in situ (DCIS) accounts for 20% of all newly diagnosed breast cancers. Mastectomy was once the gold standard for the treatment of DCIS; however, breast-conserving surgery (BCS) has been adopted as the treatment of choice for patients with small, screen-detected lesions. Both adjuvant radiation and hormonal therapy following BCS have been demonstrated in randomized trials to reduce the risk of invasive recurrence, but neither affects survival. With the variety of surgical and adjuvant treatment options available, there has been great interest in tailoring the treatment to the individual, with the goal of optimizing the balance of risks and benefits according to the values and priorities of the woman herself. Prospective studies of women with “low-risk” DCIS have successfully identified women at lower than average risk, but have not achieved the goal of identifying a subset of women with DCIS at minimal risk of recurrence after surgical excision alone.
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            Management of borderline ovarian tumors.

            Borderline ovarian tumors (BOT) are epithelial tumors of the ovaries with both malignant and non-malignant aspects. On the one hand, they are characterized by cellular proliferation and nuclear atypia but, on the other hand, they usually do not show infiltrative growth pattern. Balancing radicality between oncologic safety and treatment burden has already led to remarkable changes in the management pattern over the last decades and is still a challenging task.
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              Serrated polyps and the risk of synchronous colorectal advanced neoplasia: a systematic review and meta-analysis.

              Serrated polyps of the colon comprise a heterogeneous group of lesions with distinct histological and malignant features. The presence of serrated polyps has been associated with synchronous advanced neoplasia, although the magnitude of this relationship is unclear.
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                Author and article information

                Journal
                JAMA Oncology
                JAMA Oncol
                American Medical Association (AMA)
                2374-2437
                June 01 2019
                June 01 2019
                : 5
                : 6
                : 784
                Affiliations
                [1 ]Cancer Therapy Evaluation Program, National Cancer Institute, Bethesda, Maryland
                Article
                10.1001/jamaoncol.2019.0053
                a54e57d3-88b0-4c85-bb3e-a70e9aa7db3a
                © 2019
                History

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