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      Which parameters of beat-to-beat blood pressure and variability best predict early outcome after acute ischemic stroke?

      Stroke; a Journal of Cerebral Circulation
      Acute Disease, Adult, Aged, Aged, 80 and over, Blood Pressure, Blood Pressure Determination, methods, Female, Humans, Male, Middle Aged, Predictive Value of Tests, Prognosis, Stroke, physiopathology

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          Abstract

          In hypertensive populations, increasing blood pressure (BP) levels and BP variability (BPV) are associated with a greater incidence of target organ damage. After stroke, elevated 24-hour BP levels predict a poor outcome, although it is uncertain whether shorter-length BP recordings assessing mean BP levels and BPV have a similar predictive role. The objectives of this study were to compare the different measures of beat-to-beat BP and BPV on outcome after acute ischemic stroke and assess whether these parameters were affected by stroke subtype. Ninety-two consecutive admissions with a CT-confirmed diagnosis of acute ischemic stroke were recruited, of whom 54 had cortical infarction, 29 subcortical, and 9 posterior circulation infarction. Casual and two 5-minute recordings of beat-to-beat BP (Finapres, Ohmeda) were made under standardized conditions within 72 hours of ictus, with mean BP levels taken as the average of this 10-minute recording and BPV as the standard deviation. Outcome was assessed at 30 days as dead/dependent or independent (Rankin

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