For Publishers
DiscoveryMetadataPeer reviewHostingPublishing
For Researchers
JoinPublishReviewCollect
Register
Blog
About
Search
Advanced search
My ScienceOpen
Search
For Publishers
For Researchers
Blog
About
23
views
0
references
 Top references
cited by
842
    
0 reviews
 Review
0
comments
 Comment
0
recommends
+1 Recommend
0 collections
    0
    shares
      4,098
      similar
       All similar
      • Record: found
      • Abstract: not found
      • Article: not found

      Pembrolizumab in Microsatellite-Instability–High Advanced Colorectal Cancer

      Read this article at

      ScienceOpenPublisherPubMed
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          <p class="first" id="d26238e218">Programmed death 1 (PD-1) blockade has clinical benefit in microsatellite-instability-high (MSI-H) or mismatch-repair-deficient (dMMR) tumors after previous therapy. The efficacy of PD-1 blockade as compared with chemotherapy as first-line therapy for MSI-H-dMMR advanced or metastatic colorectal cancer is unknown. </p>

          Related collections

          Author and article information

          Contributors
          Journal
          Title: New England Journal of Medicine
          Abbreviated Title: N Engl J Med
          Publisher: Massachusetts Medical Society
          ISSN (Print): 0028-4793
          ISSN (Electronic): 1533-4406
          Publication date Created: December 03 2020
          Publication date (Print): December 03 2020
          Volume: 383
          Issue: 23
          Pages: 2207-2218
          Affiliations
          [1 ]From Sorbonne Université and Hôpital Saint Antoine, Paris (T.A.), Bordeaux University Hospital, Bordeaux (D.S.), and Léon Bérard Center, Lyon (C.F.) — all in France; University College Hospital, NHS Foundation Trust, London (K.-K.S.); Asan Medical Center, University of Ulsan, Seoul, South Korea (T.W.K.); Herlev and Gentofte Hospital, Herlev (B.V.J.), and University Hospital of Southern Denmark, Vejle (L.H.J.) — both in Denmark; Amsterdam University Medical Center, University of Amsterdam, Amsterdam (C.P....
          Article
          DOI: 10.1056/NEJMoa2017699
          PubMed ID: 33264544
          SO-VID: a6034303-135f-45c3-9b5b-76e254ca839c
          Copyright © © 2020
          License:

          http://www.nejmgroup.org/legal/terms-of-use.htm

          History

          Data availability:

          Comments

          Comment on this article

          scite_

          Similar content4,098

          See all similar

          Cited by839

          See all cited by