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      Reply: What Is the Ideal Neophallus? Response to Frey et al. (2017): An Update on Genital Reconstruction Options for the Female-to-Male Transgender Patient: A Review of the Literature

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      , MD, , BA, , MD, , MD
      Plastic and Reconstructive Surgery Global Open
      Wolters Kluwer Health

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          Abstract

          We would like to thank Dr. Elfering et al. 1 for their comments regarding our article “An Update on Genital Reconstruction Options for the Female-to-Male Transgender Patient: A Review of the Literature.” Like these authors, we agree that there is no solitary, ideal neophallus and that goals for each procedure should be individualized to each unique patient. By discussing the characteristics of the “ideal” neophallus set forth by Drs. Hage and De Graaf 2 in 1993, we address the aspects of neophallus creation that are commonly thought to be most fundamental in the construction of a functional and aesthetic neophallus. With this in mind, some patients may prioritize certain of these characteristics or even other characteristics not listed by Drs. Hage and De Graaf, in their reconstruction. Although standing urination may be paramount for 1 patient, limitation of donor-site morbidity may be for another. With this in mind, each treatment plan and reconstructive modality should be tailored to each individual presenting for neophallus creation. It is with this in mind that we call for improved patient-reported outcome measures examining which reconstruction best addresses each aspect as well as validated tools to assess what aspects are most important to patients themselves. The lack of such information in the literature is further addressed in our article examining comparative outcomes with metoidioplasty and radial free forearm flap phalloplasty. 3 We concur that the question you pose, “To what degree does a surgical treatment fulfill the need and expectations of a well-informed transgender man undergoing this treatment?” is perhaps the most imperative as we move toward patient-centered transgender care. We look forward to learning more about the decision-making tool that your institution is developing along with outcomes associated with its utilization. Again, we would like to thank you for your comments regarding our article. It is through multi-institutional and cross-cultural collaboration that we can continue to improve outcomes in gender conforming surgery, providing the highest quality, evidence-based, and individualized care to gender nonconforming individuals moving forward.

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          Most cited references3

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          A Systematic Review of Metoidioplasty and Radial Forearm Flap Phalloplasty in Female-to-male Transgender Genital Reconstruction: Is the “Ideal” Neophallus an Achievable Goal?

          Introduction: The complex anatomy and function of the native penis is difficult to surgically replicate. Metoidioplasty and radial forearm flap phalloplasty (RFFP) are the 2 most commonly utilized procedures for transgender neophallus construction. Methods: A MEDLINE search for metoidioplasty and RFFP in female-to-male genital reconstruction was performed. Primary outcome measures were subsequently compared. A systematic review was planned in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyse guidelines. Grading of Recommendations Assessment, Development and Evaluation (GRADE) was utilized to evaluate the quality of evidence. Results: Using Population, Intervention, Comparison and Outcomes tool criteria, a total of 188 articles were identified; 7 articles related to metoidioplasty and 11 articles related to RFFP met inclusion criteria. The GRADE quality of evidence was low to very low for all included studies. In studies examining metoidioplasty, the average study size and length of follow-up were 54 patients and 4.6 years, respectively (1 study did not report [NR]). Eighty-eight percent underwent a single-stage reconstruction (0 NR), 87% reported an aesthetic neophallus (3 NR), and 100% reported erogenous sensation (2 NR). Fifty-one percent of patients reported successful intercourse (3 NR), and 89% of patients achieved standing micturition (3 NR). In studies examining RFFP, the average study size and follow-up were 60.4 patients and 6.23 years, respectively (6 NR). No patients underwent single-stage reconstructions (8 NR). Seventy percent of patients reported a satisfactorily aesthetic neophallus (4 NR), and 69% reported erogenous sensation (6 NR). Forty-three percent reported successful penetration of partner during intercourse (6 NR), and 89% achieved standing micturition (6 NR). Compared with RFFP, metoidioplasty was significantly more likely to be completed in a single stage (P < 0.0001), have an aesthetic result (P = 0.0002), maintain erogenous sensation (P < 0.0001), achieve standing micturition (P = 0.001), and have a lower overall complication rate (P = 0.02). Conclusions: Although the current literature suggests that metoidioplasty is more likely to yield an “ideal” neophallus compared with RFFP, any conclusion is severely limited by the low quality of available evidence.
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            Addressing the ideal requirements by free flap phalloplasty: some reflections on refinements of technique.

            Ideally, in phalloplasty one should aim at 1) a one-stage procedure that can be predictably reproduced, 2) creation of a competent neo-urethra to allow for voiding while standing, 3) return of both tactile and erogenous sensibility, 4) enough bulk to tolerate the insertion of a prosthetic stiffener, and 5) a result that is aesthetically acceptable to the patient. We consider 6) minimal scarring or disfigurement, and 7) no functional loss in the donor area further requirements for any ideal procedure. Thanks to ongoing refinements, microsurgical free flap phalloplasty techniques lead to the best results, both functionally and cosmetically. These refinements are presented and discussed, as are our experiences applying them.
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              What is the ideal neophallus? Response to Frey et al. (2017): an update on genital reconstruction options for the female-to-male transgender patient: a review of the literature.

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                Author and article information

                Journal
                Plast Reconstr Surg Glob Open
                Plast Reconstr Surg Glob Open
                GOX
                Plastic and Reconstructive Surgery Global Open
                Wolters Kluwer Health
                2169-7574
                30 August 2017
                August 2017
                : 5
                : 8
                : e1451
                Affiliations
                From the Hansjörg Wyss Department of Plastic Surgery, NYU Langone Medical Center, New York, N.Y.
                Author notes
                Alexes Hazen, MD, Hansjörg Wyss Department of Plastic Surgery, NYU Langone Medical Center, 550 1st Avenue, New York, NY 10016, E-mail: Alexes.Hazen@ 123456nyumc.org
                Article
                00024
                10.1097/GOX.0000000000001451
                5585443
                a62045e8-99ce-4c47-bd9c-c4833fd56d3e
                Copyright © 2017 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of The American Society of Plastic Surgeons.

                This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.

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